Share

October 25, 2016; 87 (17) Article

Physical activity and the incidence of multiple sclerosis

Kirsten S. Dorans, Jennifer Massa, Tanuja Chitnis, Alberto Ascherio, Kassandra L. Munger
First published September 28, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003260
Full PDF
Citation
Permissions

Make Comment

See Comments

Downloads
369

Share

Article Information

vol. 87 no. 17 1770-1776
DOI: 
https://doi.org/10.1212/WNL.0000000000003260
PubMed: 
27683852
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received March 11, 2016
  • Accepted in final form July 6, 2016
  • First Published September 28, 2016.

Article Versions

Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Kirsten S. Dorans, ScD,
    2. Jennifer Massa, ScD,
    3. Tanuja Chitnis, MD,
    4. Alberto Ascherio, MD, DrPH and
    5. Kassandra L. Munger, ScD
  1. Kirsten S. Dorans, ScD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. (1) Non-profit: American Heart Association, Epidemiology and Prevention Early Career Travel Grant

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) National Institutes of Health, T32 HL007575, Trainee, 2011-2016 (2) National Institutes of Health, R01NS046635, Received support from grant, 2012-2013

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. (1) Antarctic Science Ltd. (Spouse received funding in 2015. It is

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Jennifer Massa, ScD,
    3. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Tanuja Chitnis, MD,
    4. Scientific Advisory Boards:

    1. Dr. Chitnis has served on clinical trial advisory boards for Novartis Pharmaceuticals, and Genzyme-Sanofi.

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. Dr. Chitnis has served as a one-time consultant for Biogen-Idec, Novartis, Genzyme-Sanofi and Genentech-Roche.

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Dr. Chitnis receives research support from (1) EMD-Serono, (2) Novartis, (3) Biogen (4) Verily, in the form of Independent Investigator Awards.

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Dr. Chitnis receives research support from the National Multiple Sclerosis Society, the Peabody Foundation, the Consortium for MS Centers and the Guthy-Jackson Charitable Foundation.

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Alberto Ascherio, MD, DrPH and
    5. Scientific Advisory Boards:

    1. Michael J Fox Foundation 2005-present Bayer Healthcare 2014

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. Roche, speaker honorarium, 2012

    Editorial Boards:

    1. 1) Annals of Neurology, Associate Editor 2) Multiple Sclerosis and Related Disorders, Associate Editor 3) Journal of Parkinson Disease, Associate Editor

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH R01 NS061858; 2009-2014; Role: PI NIH R01 NS071082; 2012-2014; Role: PI NIH R01 NS046635; 2008-2015; Role: PI NIH R01 ES019188; 2010-2015; Role: Co-Investigator NIH R01 NS072494; 2011-2014; Role: Co-Investigator NIH R01 NS073633; 2011-present; Role: PI DoD W81XWH-14-1-0131; 2014-present; Role: PI NIH R01 NS045893; 2013-present; Role: PI NIH 1U01NS-90259; 2015-present; Role: Co-Investigator NIH R01 NS089619-01A1; 2015-present; Role: PI NIH R01 NS097723; 2016-present; Role: Co-Investigator

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. ALS Therapy Alliance - No award number; 2012-2014; Role: PI NMSS RG4875A/1; 2013-2015; Role: PI NMSS RG5146-A-1; 2014-present; Role: Co-Investigator NMSS RG1501-03068; 2015-present; Role: Co-Investigator

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  5. Kassandra L. Munger, ScD
    6. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. 1) Travel/honorarium. Sponsor: Croatian International Conference on Multiple Sclerosis and Related Autoimmune Disorders. Invited Speaker, Zagreb, Croatia March 5-7, 2015 2) Travel/honorarium. Sponsor: American Society for Experimental NeuroTherapeutics. Invited Speaker, Bethesda MD March 19, 2016

    Editorial Boards:

    1. 1) Multiple Sclerosis Journal, Editorial Board member, 2013-present

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH-NINDS, 1 R01 NS046635, Co-investigator, 6/1/08-present

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. 1) National Multiple Sclerosis Society

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Departments of Epidemiology (K.S.D., A.A.) and Nutrition (J.M., A.A., K.L.M.), Harvard T.H. Chan School of Public Health; Cardiovascular Epidemiology Research Unit, Department of Medicine, Beth Israel Deaconess Medical Center (K.S.D.), Channing Division of Network Medicine, Department of Medicine (A.A.), and Partners Multiple Sclerosis Center, Department of Neurology (T.C.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
  1. Correspondence to Dr. Munger: kgorham{at}hsph.harvard.edu
View Full Text

Article usage

Article usage: September 2016 to December 2022

AbstractFullPdfSource
Sep 2016603015Highwire
Oct 201635853178Highwire
Nov 20168241625Highwire
Dec 2016347211Highwire
Jan 201717543Highwire
Feb 201718226Highwire
Mar 20179255Highwire
Apr 201715612Highwire
May 20179120Highwire
Jun 20176821Highwire
Jul 20174801Highwire
Aug 20175213Highwire
Sep 20174737Highwire
Oct 20175978Highwire
Oct 2017111pmc
Nov 20175424Highwire
Nov 201782627pmc
Dec 20173801Highwire
Jan 20186233Highwire
Feb 20182844Highwire
Mar 20184983Highwire
Apr 20182710Highwire
Apr 2018102824pmc
May 20183401Highwire
Jun 20184021Highwire
Jun 201882226pmc
Jul 20184200Highwire
Aug 20184100Highwire
Aug 201833540pmc
Sep 20183933Highwire
Oct 20182911Highwire
Nov 20186543Highwire
Dec 20189511Highwire
Jan 20193232Highwire
Feb 20193512Highwire
Mar 20193110Highwire
Apr 20192602Highwire
May 20192600Highwire
Jun 20191800Highwire
Jul 20191900Highwire
Aug 20192410Highwire
Sep 20192141Highwire
Oct 20194631Highwire
Nov 20193011Highwire
Dec 20191500Highwire
Jan 20204122Highwire
Feb 20201800Highwire
Mar 20203210Highwire
Apr 20203500Highwire
May 20202010Highwire
Jun 20201410Highwire
Jul 20205010Highwire
Aug 20201801Highwire
Sep 20206601Highwire
Oct 20203722Highwire
Nov 20205356Highwire
Dec 20205843Highwire
Jan 20213200Highwire
Feb 20213310Highwire
Mar 20214223Highwire
Apr 20212200Highwire
May 20213411Highwire
Jun 20212610Highwire
Jul 20215021Highwire
Aug 20212711Highwire
Sep 20213212Highwire
Oct 20213122Highwire
Nov 20215648Highwire
Dec 20213911Highwire
Jan 20224721Highwire
Feb 20223700Highwire
Mar 20223923Highwire
Apr 20226142Highwire
May 20225100Highwire
Jun 20223200Highwire
Jul 20223311Highwire
Aug 20224154Highwire
Sep 20222611Highwire
Oct 20222353Highwire
Nov 20222611Highwire
Dec 20223812Highwire

Cited By...

Letters: Rapid online correspondence

No comments have been published for this article.
Comment

REQUIREMENTS

If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org

Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.

If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.

Submission specifications:

  • Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
  • Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
  • Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Publishing Agreement Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top

More Online

CME Course

Topics Discussed

Alert Me