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November 22, 2016; 87 (21) Article

Predicting survival after acute civilian penetrating brain injuries

The SPIN score

Susanne Muehlschlegel, Didem Ayturk, Aditi Ahlawat, Saef Izzy, Thomas M. Scalea, Deborah M. Stein, Timothy Emhoff, Kevin N. Sheth
First published October 26, 2016, DOI: https://doi.org/10.1212/WNL.0000000000003355
Susanne Muehlschlegel
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Didem Ayturk
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Aditi Ahlawat
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Saef Izzy
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Thomas M. Scalea
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Deborah M. Stein
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Timothy Emhoff
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Kevin N. Sheth
From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
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Full PDF
Citation
Predicting survival after acute civilian penetrating brain injuries
The SPIN score
Susanne Muehlschlegel, Didem Ayturk, Aditi Ahlawat, Saef Izzy, Thomas M. Scalea, Deborah M. Stein, Timothy Emhoff, Kevin N. Sheth
Neurology Nov 2016, 87 (21) 2244-2253; DOI: 10.1212/WNL.0000000000003355

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Article Information

vol. 87 no. 21 2244-2253
DOI: 
https://doi.org/10.1212/WNL.0000000000003355
PubMed: 
27784772

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received April 1, 2016
  • Accepted in final form August 11, 2016
  • First Published October 26, 2016.

Article Versions

  • Previous version (October 26, 2016 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Susanne Muehlschlegel, MD, MPH,
    2. Didem Ayturk, MS,
    3. Aditi Ahlawat, BS,
    4. Saef Izzy, MD,
    5. Thomas M. Scalea, MD,
    6. Deborah M. Stein, MD, MPH,
    7. Timothy Emhoff, MD and
    8. Kevin N. Sheth, MD
  1. Susanne Muehlschlegel, MD, MPH,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health and Human Development, 5K23HD080971, PI (Muehlschlegel, S), 2015-2020 (2) NATIONAL HEART, LUNG, AND BLOOD INSTITUTE, 5R01HL118266, PI (Muehlschlegel, JD), 2013-2018 (husband)

    Research Support, Academic Entities:
    1. (1) University of Massachusetts Faculty Scholar Award, PI, 2011-2013

    Research Support, Foundations and Societies:
    1. (1) American Heart Association/American Stroke Association, 09SDG2030022-02, PI, 2009-2013

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Didem Ayturk, MS,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Aditi Ahlawat, BS,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Saef Izzy, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Thomas M. Scalea, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Deborah M. Stein, MD, MPH,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. USAF - Grant - monies paid to my institution.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. Decisio Health, Inc. - Serve as an advisor for which I will be reimbursed travel, if and when that occurs.

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Timothy Emhoff, MD and
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Kevin N. Sheth, MD
  16. Scientific Advisory Boards:
    1. Novartis

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. (1) Neurotherapeutics, Section Edtior, Neuro-Critical Care Section, 2011 (2) Current Treatment Options in Neurology, Section Editor, 2009-present (3) Editorial Board, Neurology Today (4) Editorial Board, Neurosurgery (5) Editorial Board, Neurocritical Care (6) Editorial Board, Stroke (7) Edtorial Board, Neurology

    Patents:
    1. Provisional patent (1) Stroke detection technology

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Remedy Pharmaceuticals, Bard

    Research Support, Government Entities:
    1. (1) US Army, (2) NIH, (3) AHA

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. American Academy of Neurology Clinical Research Fellowship, American Heart Association Passano Foundation

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. Legal consultant

  1. From the Departments of Neurology (Neurocritical Care) (S.M., A.A.), Surgery (S.M., D.A., T.E.), and Anesthesia/Critical Care (S.M.), University of Massachusetts Medical School, Worcester; Department of Neurology (Division of Neurocritical Care) (S.I.), Massachusetts General Hospital and Brigham & Women's Hospital, Harvard Medical School, Boston; Department of Surgery (T.M.S., D.M.S.), R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore; and Departments of Neurology (Neurocritical Care and Emergency Neurology) (K.N.S.) and Neurosurgery (K.N.S.), Yale University, New Haven, CT.
  1. Correspondence to Dr. Muehlschlegel: susanne.muehlschlegel{at}umassmemorial.org
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