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August 09, 2016; 87 (6) Article

Type 2 diabetes mellitus is associated with brain atrophy and hypometabolism in the ADNI cohort

Wei Li, Shannon L. Risacher, Edgar Huang, Andrew J. Saykin, For the Alzheimer's Disease Neuroimaging Initiative
First published July 6, 2016, DOI: https://doi.org/10.1212/WNL.0000000000002950
Wei Li
From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
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Shannon L. Risacher
From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
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Edgar Huang
From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
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Andrew J. Saykin
From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
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From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
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Type 2 diabetes mellitus is associated with brain atrophy and hypometabolism in the ADNI cohort
Wei Li, Shannon L. Risacher, Edgar Huang, Andrew J. Saykin, For the Alzheimer's Disease Neuroimaging Initiative
Neurology Aug 2016, 87 (6) 595-600; DOI: 10.1212/WNL.0000000000002950

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Article Information

vol. 87 no. 6 595-600
DOI: 
https://doi.org/10.1212/WNL.0000000000002950
PubMed: 
27385744

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received December 20, 2015
  • Accepted in final form April 22, 2016
  • First Published July 6, 2016.

Article Versions

  • Previous version (July 6, 2016 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2016 American Academy of Neurology

Author Disclosures

    1. Wei Li, MD, PhD,
    2. Shannon L. Risacher, PhD,
    3. Edgar Huang, PhD,
    4. Andrew J. Saykin, PsyD;
    5. For the Alzheimer's Disease Neuroimaging Initiative
  1. Wei Li, MD, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Shannon L. Risacher, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Alzheimer's Association

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Edgar Huang, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Andrew J. Saykin, PsyD;
  8. Scientific Advisory Boards:
    1. (1) Commercial: Siemens Healthcare; Eli Lilly

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1) Commercial: Siemens Healthcare and Eli Lilly travel and speaker honoraria

    Editorial Boards:
    1. (1) Brain Imaging and Behavior, a Springer Journal, Editor-in-Chief, 2006-present.

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Commercial: (1) Arkley Biotek, (2) Eli Lilly, (3) Siemens Healthcare.

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) Siemens Medical Solutions, investigator-initiated research project support; (2) Welch Allyn, Inc., investigator-initiated research project support.

    Research Support, Government Entities:
    1. NIH: R01 AG19771 (PI), R01 CA101318 (PI); R01 LM011360 (MPI); U01 AG032984 and RC2 AG036535 (Genetics Core Leader), P30 AG10133 (PI and Neuroimaging Core Leader).

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) Foundation for the NIH (FNIH): PI & co-PI of ADNI related genetics projects

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. For the Alzheimer's Disease Neuroimaging Initiative
  1. From Master of Physician Assistant Studies, School of Health and Rehabilitation Sciences (W.L.), and School of Informatics and Computing (E.H.), Indiana University Purdue University Indianapolis; and Center for Neuroimaging (S.L.R., A.J.S.), Department of Radiology and Imaging Sciences, and Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN.
  1. Correspondence to Dr. Li: wl23{at}iu.edu
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