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Parkinson disease (PD) is a chronic progressive neurodegenerative disorder with a relatively high incidence.1 PD seems to result from a complicated interplay of genetic and environmental factors affecting numerous fundamental cellular processes.2 However, the ultimate cause of loss of dopaminergic neurons in the substantia nigra pars compacta remains to be determined.2 An outright definitive cure for the disease remains elusive, leaving both patients and their caregivers with the challenge of living with a chronic medical condition that affects their health-related quality of life.2 It is therefore imperative to focus research efforts on the search for the etiology of this condition.
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See page 1630
- © 2017 American Academy of Neurology
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