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November 28, 2017; 89 (22) ArticleOpen Access

Early weight loss in parkinsonism predicts poor outcomes

Evidence from an incident cohort study

Kirsten Cumming, Angus D. Macleod, Phyo K. Myint, Carl E. Counsell
First published October 27, 2017, DOI: https://doi.org/10.1212/WNL.0000000000004691
Kirsten Cumming
From the School of Medicine (K.C.), Medical Sciences & Nutrition, and Chronic Disease Research Group (A.D.M., C.E.C.) and Ageing Clinical & Experimental Research Team (P.K.M.), Institute of Applied Health Sciences, University of Aberdeen, Scotland.
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Angus D. Macleod
From the School of Medicine (K.C.), Medical Sciences & Nutrition, and Chronic Disease Research Group (A.D.M., C.E.C.) and Ageing Clinical & Experimental Research Team (P.K.M.), Institute of Applied Health Sciences, University of Aberdeen, Scotland.
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Phyo K. Myint
From the School of Medicine (K.C.), Medical Sciences & Nutrition, and Chronic Disease Research Group (A.D.M., C.E.C.) and Ageing Clinical & Experimental Research Team (P.K.M.), Institute of Applied Health Sciences, University of Aberdeen, Scotland.
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Carl E. Counsell
From the School of Medicine (K.C.), Medical Sciences & Nutrition, and Chronic Disease Research Group (A.D.M., C.E.C.) and Ageing Clinical & Experimental Research Team (P.K.M.), Institute of Applied Health Sciences, University of Aberdeen, Scotland.
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Citation
Early weight loss in parkinsonism predicts poor outcomes
Evidence from an incident cohort study
Kirsten Cumming, Angus D. Macleod, Phyo K. Myint, Carl E. Counsell
Neurology Nov 2017, 89 (22) 2254-2261; DOI: 10.1212/WNL.0000000000004691

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    Figure 1 Study flowchart

    Flowchart of Parkinsonism Incidence in North-East Scotland (PINE) study participants.

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    Figure 2 Weight change over time in controls and those with PD and atypical parkinsonian syndromes

    Adjusted yearly estimates of mean weight in kilograms from baseline (from patients' diagnosis and from control recruitment) in controls, patients with idiopathic PD, and those with atypical parkinsonian syndromes. Bars represent the 95% confidence intervals for each data point. PD = Parkinson disease.

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  • Japanese Translation

    Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
    © 2018 American Academy of Neurology.

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    • Japanese Translation - PDF

Letters: Rapid online correspondence

  • Author response: Early weight loss in neurodegenerative disorders could be related to increased protein metabolism in the brain
    • Angus D. Macleod, Clinical Lecturer in Neurology, University of Aberdeen
    • Phyo K. Myint, Professor of Old Age Medicine, University of Aberdeen
    • Carl E. Counsell, Reader (Clinical) in Neurology, University of Aberdeen
    Submitted April 13, 2018
  • Early weight loss in neurodegenerative disorders could be related to increased protein metabolism in the brain
    • Lucio Marinelli, Assistant Professor of Neurology, University of Genovalucio.marinelli@unige.it
    Submitted November 09, 2017
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