Regional oxygen extraction predicts border zone vulnerability to stroke in sickle cell disease
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Article Information
- Received March 23, 2017
- Accepted in final form December 5, 2017
- First Published March 2, 2018.
Article Versions
- Previous version (March 2, 2018 - 12:45).
- You are viewing the most recent version of this article.
Author Disclosures
- Melanie E. Fields, MD, MSCI*,
- Kristin P. Guilliams, MD, MSCI*,
- Dustin K. Ragan, PhD,
- Michael M. Binkley, MS,
- Cihat Eldeniz, PhD,
- Yasheng Chen, DSc,
- Monica L. Hulbert, MD,
- Robert C. McKinstry, MD, PhD,
- Joshua S. Shimony, MD, PhD,
- Katie D. Vo, MD,
- Allan Doctor, MD,
- Hongyu An, DSc,
- Andria L. Ford, MD, MSCI† and
- Jin-Moo Lee, MD, PhD†
- Melanie E. Fields, MD, MSCI*,
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1. NIH NHLBI, K12 5K12HL087107, Scholar, 8/1/2014- 5/31/2017 2. NIH NHLBI, 1K23HL136904-01, PI, 6/1/2017- 5/31/2021 3. NIH NCATS UL1TR000448, PI - Research Forum for Child Health Supplemental Funding Award, 04/01/2013 - 03/31/2017 4. NIH NHCHD U54 HD087011, PI - Washington University Intellectual and Developmental Disabilities Research Center, 5/15/2016- 11/15/2017 5. NIH NCATS UL1TR000448, PI - Foundation for Barnes-Jewish Hospital and Washington University Institute of Clinical and Translational Sciences, 7/1/2017- 6/30/2018
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1. Mallinckrodt Institute of Radiology Pilot Study Award, 2/1/2015- 3/31/2016 2. American Society of Hematology Fellow Scholar Award, 7/1/2017- 6/30/2019 Stock/Stock Options, Medical Equipment & Materials: 1. Equity ownership in Proclara Biosciences.
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- Kristin P. Guilliams, MD, MSCI*,
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Asian and Oceanian Congress of Child Neurology, funding for travel to speak at conference
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- Dustin K. Ragan, PhD,
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- Michael M. Binkley, MS,
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My Ph.D. fellowship is sponsored by the NIH using the training program for a separate project in pulmonary medicine for the development of a microfluidic diagnostic test for COPD. Grant T32HL007317-39, graduate student trainee, 1 year, National Institutes of Health
Washington University in St. Louis, Department of Mechanical Engineering and Material Science
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- Cihat Eldeniz, PhD,
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(1) [Purpose: Obtaining images without motion blurring at multiple respiratory phases.] Free-breathing and self-navigated MRI method for deformable motion derivation US provisional application # 62/446,193 (2) [Purpose: Obtaining an attenuation correction map for simultaneous PET/MR.] Dual Flip Angle Multi-Echo Ultra-Short Echo Time (DUFA- MUTE) Magnetic Resonance Imaging (MRI) Systems and Methods US provisional application # 62/445,817
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National Institute of Health, P30 NS098577, PI: Hongyu An, Role: Postdoctoral Research Associate, Years: 2 years [perhaps ???]
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- Yasheng Chen, DSc,
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The NIH HL129241, R01NS085419, R01NS082561, P30NS098577
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- Monica L. Hulbert, MD,
Sickle Cell Transplant Alliance for Research
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Pediatric Blood and Cancer, editorial board member, 20116-present
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My husband is employed at Pfizer, Inc as a quality control scientist; 2012- present
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State of Missouri, grant # C3143345003, PI, 2012-2018 HRSA, 2U1EMC278650400, co-investigator, 2014-2017 NIH, R01 HL129241-02, co-investigator, 2015-2020 NIH, 5U1EMC278650300, co-infestigator, 2017-2022 Stock/Stock Options, Medical Equipment & Materials: stock in Pfizer, Inc as part of my husband's employment/retirement plan
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- Robert C. McKinstry, MD, PhD,
Guerbet, LLC
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Siemens Healthcare - travel, meals and honoraria. Philips - travel and meals.
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NIH 2R01HD055741-11 Investigator 07/01/2007 ? 7/31/2022 NIH 2UL1TR000448-06 Core Director 09/17/2007 ? 05/31/2017 NIH 1UL1TR002345-01 Core Director 01/19/2017 - 02/28/2022 NIH 1U01NS092764-01A1 Investigator 09/30/2016 ? 06/30/2021
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March of Dimes Investigator 11/01/2014 ? 10/31/2019
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- Joshua S. Shimony, MD, PhD,
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(1) NIH R01 CA203861 PI (2) NIH R01 MH114970 PI (3) NIH U54 HD087011 Co-I
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I routinely testify in legal cases, mostly related to Traumatic brain injury or Injured infant cases. These do not relate to the current manuscript.
- Katie D. Vo, MD,
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- Allan Doctor, MD,
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Biogen, Inc.
Biogen, Inc.
Pediatric Critical Care Medicine (past 5Y) (editorial board)
2005 U.S. Patent # 7,763,472. Methods for Identifying and Measuring S-Nitrosothiol Bonds in Heme-containing Cells and Molecules. 2016 U.S. Patent # 9,486,508. Blood Substitute Composition and Method of Use (NanoCrit). Also filed in: Europe, Australia, Canada, Japan and South Africa.
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Entegrion, Inc. Terumo, BCT KaloCyte, Inc.
NIH/NIGMS/NHLBI 1R01GM113838; PI 2015-20 NIH/NHLBI 1R42HL135965-01A1; PI 2017-20 DoD GRANT12234110; PI 2017-20
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Children?s Discovery Institute, CH-LI-2013-420; PI 2013-17
KaloCyte, Inc.
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KaloCyte, Inc. Stock/Stock Options, Medical Equipment & Materials: KaloCyte, Inc.
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- Hongyu An, DSc,
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NIH, R01NS082561, PI, 04/01/14-03/31/19 NIH, 1P30NS098577, PI, 07/01/16-06/30/20 NIH, 1R01HL129241-01, Co-I, 08/01/15-05/31/19
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- Andria L. Ford, MD, MSCI† and
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NIH NHLBI, R01HL129241, PI, 2015-2020 NIH UL1 TR000448, Washington University Institute of Clinical and Translational Science, Project PI, 2015-2016
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- Jin-Moo Lee, MD, PhD†
DSMB for the CN-105 CATCH Trial, AegisCN LLC
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Translational Stroke Research, Editorial Board, 2012- present
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(1) NIH NINDS R01NS084028 PI 7/17/13-6/30/18 (2) NIH NINDS R01NS085419 PI 4/1/14-3/31/19 (3) NIH NIA R21AG055333 PI 3/15/17-2/28/19 (4) NIH NINDS R01NS094692 PI 8/1/17-5/31/22
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Barnes-Jewish Hospital Foundation
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- From the Division of Pediatric Hematology/Oncology (M.E.F., M.L.H.), Division of Pediatric Neurology (K.P.G.), Division of Pediatric Critical Care Medicine (K.P.G., A.D.), Department of Neurology (D.K.R., Y.C., A.L.F., J.-M.L.), and Mallinckrodt Institute of Radiology (C.E., R.C.M., J.S.S., K.D.V., H.A., J.-M.L.), Washington University School of Medicine; and Department of Biomedical Engineering (M.B.M., J.-M.L.), Washington University, St. Louis, MO.
- Correspondence
Dr. Lee leejm{at}neuro.wustl.edu or Dr. Ford forda{at}wustl.edu
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