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April 24, 2018; 90 (17) Article

Aminophylline for treatment of postdural puncture headache

A randomized clinical trial

Chuanjie Wu, Dongsheng Guan, Ming Ren, Zhengfei Ma, Changming Wan, Yinglin Cui, Ping Zhong, Wenbo Zhao, Chuanhui Li, Feng Yan, Jinqiu Xie, Fang Xue, Yajun Lian, Hongbo Liu, Cui Wang, Xunming Ji, Nanchang Xie
First published March 23, 2018, DOI: https://doi.org/10.1212/WNL.0000000000005351
Chuanjie Wu
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Dongsheng Guan
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Ming Ren
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Zhengfei Ma
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Changming Wan
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Yinglin Cui
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Ping Zhong
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Wenbo Zhao
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Chuanhui Li
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Feng Yan
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Jinqiu Xie
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Fang Xue
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Yajun Lian
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Hongbo Liu
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Cui Wang
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Xunming Ji
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Nanchang Xie
From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
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Full PDF
Citation
Aminophylline for treatment of postdural puncture headache
A randomized clinical trial
Chuanjie Wu, Dongsheng Guan, Ming Ren, Zhengfei Ma, Changming Wan, Yinglin Cui, Ping Zhong, Wenbo Zhao, Chuanhui Li, Feng Yan, Jinqiu Xie, Fang Xue, Yajun Lian, Hongbo Liu, Cui Wang, Xunming Ji, Nanchang Xie
Neurology Apr 2018, 90 (17) e1523-e1529; DOI: 10.1212/WNL.0000000000005351

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Article Information

vol. 90 no. 17 e1523-e1529
DOI: 
https://doi.org/10.1212/WNL.0000000000005351
PubMed: 
29572284

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received August 28, 2017
  • Accepted in final form January 25, 2018
  • First Published March 23, 2018.

Article Versions

  • Previous version (March 23, 2018 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2018 American Academy of Neurology

Author Disclosures

    1. Chuanjie Wu, MD,
    2. Dongsheng Guan, MD,
    3. Ming Ren, MD,
    4. Zhengfei Ma, MD,
    5. Changming Wan, MD,
    6. Yinglin Cui, MD,
    7. Ping Zhong, MD,
    8. Wenbo Zhao, MD,
    9. Chuanhui Li, MD,
    10. Feng Yan, MD,
    11. Jinqiu Xie, MD,
    12. Fang Xue, MD,
    13. Yajun Lian, MD,
    14. Hongbo Liu, MD,
    15. Cui Wang, MD,
    16. Xunming Ji, MD and
    17. Nanchang Xie, MD
  1. Chuanjie Wu, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. National Natural Science Foundation of China,81701287, Lead investigator,2015-2018

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Dongsheng Guan, MD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Ming Ren, MD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Zhengfei Ma, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Changming Wan, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Yinglin Cui, MD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Ping Zhong, MD,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Wenbo Zhao, MD,
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. Chuanhui Li, MD,
  18. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  19. Feng Yan, MD,
  20. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  21. Jinqiu Xie, MD,
  22. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  23. Fang Xue, MD,
  24. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  25. Yajun Lian, MD,
  26. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  27. Hongbo Liu, MD,
  28. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  29. Cui Wang, MD,
  30. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. National Natural Science Foundation of China,81701272, Lead investigator,2014-2017

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  31. Xunming Ji, MD and
  32. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  33. Nanchang Xie, MD
  34. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. National Natural Science Foundation of China, 81571260, Lead investigator,2016-2020

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Neurology (C. Wu, Y.L., H.L., C. Wang, N.X.), First Affiliated Hospital of Zhengzhou University; Department of Neurology (D.G., Y.C.), Second Affiliated Hospital of Henan University of Traditional Chinese Medicine; Department of Neurosurgery (M.R., W.Z., C.L., F.Y., X.J.), Xuanwu Hospital Capital Medical University, Beijing; Department of Neurology (Z.M., P.Z.), Suzhou Municipal Hospital, Anhui; Department of Neurology (C. Wan, J.X.), Jinzhou Central Hospital, Liaoning; and Department of Neurology (F.X.), Second Hospital of Hebei Medical University, Shijiazhuang, China.
  1. Correspondence
    Dr. N. Xie xienanchanghn{at}163.com
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