Lymphoplasmacyte-rich meningioma involving the whole intracranial dura mater
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A 47-year-old woman presented with a 6-month history of occipital-cervical region pain, numbness of both upper limbs, and progressive bilateral hearing loss. Enhanced MRI revealed a lesion involving the intracranial dura mater and the right trigone area of the lateral ventricle (figure, A–J). Surgery to relieve the main symptoms was performed through a posterior midline approach (figure, K and L). Pathology suggested the diagnosis of lymphoplasmacyte-rich meningioma (figure, M–P). Lymphoplasmacyte-rich meningioma is a rare variant of meningioma and is categorized as a WHO grade I tumor and approximately 60 cases have been reported,1 but involvement of the entire intracranial dura mater is unusual. It is characterized by dense lymphoplasmacytic infiltration and usually treated with surgical resection1; however, total resection could not be achieved in our case. The patient received radiotherapy and postsurgery MRI at 3 months but demonstrated no progress.
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Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
↵* These authors contributed equally to this work.
- © 2018 American Academy of Neurology
Disputes & Debates: Rapid online correspondence
- Lymphoplasmacyte-rich meningioma mimicking pachymeningitis, but not due to IgG4-related disease
- Jiagang Liu, Neurosurgeon, Department of Neurosurgery, West China Hospital, Sichuan University
- , Neurosurgeon, Department of Neurosurgery, West China Hospital, Sichuan University
Published August 19, 2018 - Lymphoplasmacyte-rich meningioma mimicking pachymeningitis due to IgG4-related disease
- Nobuyoshi Fukuhara, Neurologist, Department of Neurology, Joetsu General Hospital (Joetsu, Japan)
- , Neuropathologist/Chief of Division of Neuropathology, Division of Neuropathology, Joetsu General Hospital (Joetsu, Japan)
Published July 11, 2018
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