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Abstract
Objective We studied the performance of a 15-item, health-related quality-of-life polyneuropathy scale in the clinic setting in patients with diabetic distal sensorimotor polyneuropathy (DSPN).
Methods Patients with DSPN from 11 academic sites completed a total of 231 Chronic Acquired Polyneuropathy Patient-Reported Index (CAPPRI) scales during their clinic visits. Conventional and modern psychometric analyses were performed on the completed forms.
Results Conventional and modern analyses generally indicated excellent psychometric properties of the CAPPRI in patients with DSPN. For example, the CAPPRI demonstrated unidimensionality and performed like an interval-level scale.
Conclusion Attributes of the CAPPRI for DSPN include ease of use and interpretation; unidimensionality, allowing scores to be summed; adequate coverage of disease severity; and the scale's ability to address relevant life domains. Furthermore, the CAPPRI is free and in the public domain. The CAPPRI may assist the clinician and patient with DSPN in estimating disease-specific quality of life, especially in terms of pain, sleep, psychological well-being, and everyday function. The CAPPRI may be most useful in the everyday clinical setting but merits further study in this setting, as well as the clinical trial setting.
Glossary
- CAPPRI=
- Chronic Acquired Polyneuropathy Patient-Reported Index;
- CI=
- confidence interval;
- DIF=
- differential item functioning;
- DSPN=
- distal sensorimotor polyneuropathy;
- HRQOL=
- health-related quality of life;
- INCAT=
- Inflammatory Neuropathy Cause and Treatment;
- MNSQ=
- mean square;
- ODSS=
- Overall Disability Sum Score;
- RPCM=
- Rasch partial credit model
Footnotes
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
Podcast: NPub.org/wiy6sj
- Received December 22, 2017.
- Accepted in final form March 20, 2018.
- © 2018 American Academy of Neurology
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