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January 16, 2018; 90 (3) Special Article

Practice guideline update summary: Mild cognitive impairment

Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology

Ronald C. Petersen, Oscar Lopez, Melissa J. Armstrong, Thomas S.D. Getchius, Mary Ganguli, David Gloss, Gary S. Gronseth, Daniel Marson, Tamara Pringsheim, Gregory S. Day, Mark Sager, James Stevens, Alexander Rae-Grant
First published December 27, 2017, DOI: https://doi.org/10.1212/WNL.0000000000004826
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Article Information

vol. 90 no. 3 126-135
DOI: 
https://doi.org/10.1212/WNL.0000000000004826
PubMed: 
29282327
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received February 24, 2017
  • Accepted in final form September 22, 2017
  • First Published December 27, 2017.

Article Versions

Copyright & Usage: 
Copyright © 2017 American Academy of Neurology

Author Disclosures

    1. Ronald C. Petersen, MD, PhD,
    2. Oscar Lopez, MD,
    3. Melissa J. Armstrong, MD, MSc,
    4. Thomas S.D. Getchius,
    5. Mary Ganguli, MD, MPH,
    6. David Gloss, MD, MPH&TM,
    7. Gary S. Gronseth, MD,
    8. Daniel Marson, JD, PhD,
    9. Tamara Pringsheim, MD,
    10. Gregory S. Day, MD, MSc,
    11. Mark Sager, MD,
    12. James Stevens, MD and
    13. Alexander Rae-Grant, MD
  1. Ronald C. Petersen, MD, PhD,
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. Mild Cognitive Impairment,Oxford University Press, 2003

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. (1) Roche Incorporated, (2) Merck, (3) Genentech, (4) Biogen

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. National Institute on Aging: U01-AG006786 (PI) (1986-present) P50-AG016574 (PI) (1990-present) U01-AG024904 (PI) (2004-present) U01 AG016976 (PI) (1989 ? present)

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  2. Oscar Lopez, MD,
    3. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. Lundbeck,Grifols

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIA: P50 AG05133-29; 1P01-AG025204-04

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  3. Melissa J. Armstrong, MD, MSc,
    4. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. (1) Neurology, Level of Evidence Editorial Board, 2012- current

    Patents:

    1. NONE

    Publishing Royalties:

    1. (1) Parkinson's Disease: Improving Patient Care, Oxford University Press, 2014

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. (1) American Academy of Neurology Evidence-Based Medicine Methodology Consultant

    Speakers' Bureaus:

    1. NONE

    Other activities:

    1. (1) Medscape CME (2016 writing, speaking honoraria)

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) ARHQ, K08HS024159, PI, 2015-2020

    Research Support, Academic Entities:

    1. (1) TBI Endpoints Development Initiative (2016-2017)

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  4. Thomas S.D. Getchius,
    5. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. March 2017: Received reimbursement for faculty travel expenses to the New York Academy of Medicine.

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  5. Mary Ganguli, MD, MPH,
    6. Scientific Advisory Boards:

    1. (1)DSMB for National Institute on Aging, grant # AG045157 to Indiana University,

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. (1) Alzheimer Association, travel to Alzheimer Association International Conference.

    Editorial Boards:

    1. (1) Journal of the American Geriatrics Society, Associate Editor, 2008-present. (2) International Psychogeriatrics, Associate Editor, 1996-present. (3) Alzheimer Disease and Associated Disorders, Editorial Board member, 2011-present.

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) National Institute on Aging, K07 AG044395, 2003-2013 (2) National Institute on Aging, R01 AG023651, 2013-2018

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  6. David Gloss, MD, MPH&TM,
    7. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Neurology, LOE Review Team

    Patents:

    1. NONE

    Publishing Royalties:

    1. (1) Neurology for the Specialty Boards, Lippincott Williams and Wilkins, 2006

    Employment, Commercial Entity:

    1. (1) Charleston Area Medical Center, Charleston, WV 25311

    Consultancies:

    1. (1) I am an Evidence-based medicine consultant for the American Academy of Neurology

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  7. Gary S. Gronseth, MD,
    8. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. (1) Neurology Now, Editorial advisory board, Inception- Present (2) Neurology, Associate Editor, 2013-Present

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. American Academy of Neurology

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  8. Daniel Marson, JD, PhD,
    9. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. Dr. Marson received an initial honoraria upon signing agreement for writing book entitled: (1) Clinical and Forensic Assessment of Financial Capacity; Publisher: Oxford University Press; Expected publication date 2018

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. (1) Consultant for Janssen Pharmaceuticals

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) NIH grant AG021927 (2004-present, PI) (2) Funded as ADNI site PI for AG24904 (2004-2016) (3) NIH grant AG045154; co-investigator (08/15/14-present)

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. (1) Inventor of Financial Capacity Instrument and Financial Capacity Instrument--Short Form which are both owned by UAB Research Foundation. Have received part of a licensing fee payment received by UABRF for providing the FCI-SF to a company in a clinical trial. (2) Co-inventor of CCTI assessment instrument which is owned by UAB Research Foundation. (1996-present).

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. Provided consultation: State Farm v. Kercinick (2015-2017)(expert witness for plaintiff) Fidelity National Title v. Whitley (2015)(expert witness of plaintiff)

  9. Tamara Pringsheim, MD,
    10. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Neurology Clinical Practice, Editorial Board Member, 2016, 2017 Canadian Journal of Psychiatry, Editorial Board Member, 2016, 2017

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. (1) Canadian Institutes of Health Research, Principal Investigator 2014/2015; Co-investigator 2016-2018 (2) Sick Kids Foundation, Principal Investigator, 2013-2018 (3) Alberta Mental Health Strategic Clinical Network, 2014-2016

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  10. Gregory S. Day, MD, MSc,
    11. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Serve as an ad-hoc Editor for DynaMed (online evidence- based medicine resource; 2016-ongoing) for content related to dementia.

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Avid Pharmaceuticals (provision of radiotracer for ongoing research study).

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. 1. Barnes Jewish Hospital Foundation

    Research Support, Foundations and Societies:

    1. 1. American Brain Foundation, Clinical Research Training Fellowship (2016-17) 2. Eugene M Johnson Jr, Weston Brain Institute Postdoctoral Fellowship (2015 Recipient) Stock/Stock Options, Medical Equipment & Materials: 1) Hold stocks (>$10,000) in ANI Pharmaceuticals (a generic pharmaceutical company; 2015 onward).

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  11. Mark Sager, MD,
    12. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  12. James Stevens, MD and
    13. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. NONE

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. Sanofi-Aventis, Biogen, Lilly, Flamel

    Research Support, Government Entities:

    1. NONE

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  13. Alexander Rae-Grant, MD
    14. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. NONE

    Editorial Boards:

    1. Neurology, Evidence Review Team, 2011-2017

    Patents:

    1. NONE

    Publishing Royalties:

    1. Handbook of Multiple Sclerosis, Springer Healthcare, 2010 Comprehensive review of clinical neurology, Wolters Kluwer, 2012 5 minute consult in neurology, Wolters Klower, 2012 Comprehensive review of clinical neurology second edition, LWW, 2016 Ultimate review of neurology DEMOS 2016 Multiple Sclerosis and Related disorders, DEMOS, 2014

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. NONE

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. I edit neurology chapters for dynamic medical, an online text book of medicine which is funded via library subscriptions and receive a fee for work provided. involved in a clinical trial of biotin for multiple sclerosis with MedDay (no personal remuneration)

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. CO-PI 4% effort FMRI as an imaging biomarker for preclinical Alzheimer's disease, 2013-2017 NIH grant #A6022304

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. NONE

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Department of Neurology (R.C.P.), Mayo Clinic, Rochester, MN; Department of Neurology (O.L.), University of Pittsburgh Medical Center, PA; Department of Neurology (M.J.A.), University of Florida College of Medicine, Gainesville; Heart Rhythm Society (T.S.D.G.), Washington, DC; Department of Psychiatry (M.G.), University of Pittsburgh, PA; Department of Neurology (D.G.), Charleston Area Medical Center, WV; Department of Neurology (G.S.G.), University of Kansas Medical Center, Kansas City; Department of Neurology (D.M.), University of Alabama, Birmingham; Department of Clinical Neurosciences, Psychiatry, Pediatrics and Community Health Sciences (T.P.), Cumming School of Medicine, University of Calgary, Canada; Knight Alzheimer Disease Research Center (G.S.D.), Washington University School of Medicine, St. Louis, MO; Wisconsin Alzheimer's Institute (M.S.), School of Medicine and Public Health, University of Wisconsin, Madison; Department of Neurology (J.S.), Fort Wayne Neurological Center, IN; and Department of Neurology (A.R.-G.), Cleveland Clinic, OH.
  1. Correspondence
    American Academy of Neurology guidelines{at}aan.com
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Cited By...

Disputes & Debates: Rapid online correspondence

  • Author response to Braillon: Practice guideline update summary: Mild cognitive impairment: Report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology
    • Ronald C. Petersen, Neurologist, Mayo Clinic
    • Oscar Lopez, Neurologist, University of Pittsburgh Medical Center
    • Melissa J. Armstrong, Neurologist, University of Florida College of Medicine
    • Thomas S.D. Getchius, Manager, Heart Rhythm Society
    • Mary Ganguli, Psychiatrist, Department of Psychiatry, University of Pittsburgh
    • David Gloss, Neurologist, Charleston Area Medical Center Neurology
    • Gary S. Gronseth, Neurologist, University of Kansas Medical Center
    • Daniel Marson, Clinical Neuropsychologist, University of Alabama at Birmingham
    • Tamara Pringsheim, Neurologist, Cumming School of Medicine, University of Calgary
    • Gregory S. Day, Neurologist, Knight Alzheimer Disease Research Center, Washington University School of Medicine
    • Mark Sager, Geriatrician, School of Medicine and Public Health, University of Wisconsin
    • James Stevens, Neurologist, Fort Wayne Neurological Center
    • Alexander D. Rae-Grant, Neurologist, Cleveland Clinic Neurological Institute at Lakewood Hospital
    Submitted March 01, 2018
  • RE: Author response to Valenzuela et al.
    • Ronald C. Petersen, Neurologist, Mayo Clinic
    • Oscar Lopez, Neurologist, University of Pittsburgh Medical Center
    • Melissa J. Armstrong, Neurologist, University of Florida College of Medicine
    • Thomas S.D. Getchius, Manager, Heart Rhythm Society
    • Mary Ganguli, Psychiatrist, Department of Psychiatry, University of Pittsburgh
    • David Gloss, Neurologist, Charleston Area Medical Center Neurology
    • Gary S. Gronseth, Neurologist, University of Kansas Medical Center
    • Daniel Marson, Clinical Neuropsychologist, University of Alabama at Birmingham
    • Tamara Pringsheim, Neurologist, Cumming School of Medicine, University of Calgary
    • Gregory S. Day, Neurologist, Knight Alzheimer Disease Research Center, Washington University School of Medicine
    • Mark Sager, Geriatrician, School of Medicine and Public Health, University of Wisconsin
    • James Stevens, Neurologist, Fort Wayne Neurological Center
    • Alexander D. Rae-Grant, Neurologist, Cleveland Clinic Neurological Institute at Lakewood Hospital
    Submitted February 20, 2018
  • Practice guideline update summary: Mild cognitive impairment: Report of the guideline development, dissemination, and implementation subcommittee of the American Academy of Neurology
    • Alain Braillon, Senior consultant, University Hospital, 80000 Amiens, France
    Submitted February 14, 2018
  • Author response to Drs. Wang and Cui
    • Ron C. Petersen, Neurologist, Mayo Clinic
    • Oscar Lopez, Neurologist, University of Pittsburgh Medical Center
    • Melissa J. Armstrong, Neurologist, University of Florida College of Medicine
    • Thomas S.D. Getchius, Manager, Heart Rhythm Society
    • Mary Ganguli, Psychiatrist, Department of Psychiatry, University of Pittsburgh
    • David Gloss, Neurologist, Charleston Area Medical Center Neurology
    • Gary S. Gronseth, Neurologist, University of Kansas Medical Center
    • Daniel Marson, Clinical Neuropsychologist, University of Alabama at Birmingham
    • Tamara Pringsheim, Neurologist, Cumming School of Medicine, University of Calgary
    • Gregory S. Day, Neurologist, Knight Alzheimer Disease Research Center, Washington University School of Medicine
    • Mark Sager, Geriatrician, School of Medicine and Public Health, University of Wisconsin
    • James Stevens, Neurologist, Fort Wayne Neurological Center
    • Alexander D. Rae-Grant, Neurologist, Cleveland Clinic Neurological Institute at Lakewood Hospital
    Submitted January 29, 2018
  • Concerns about cholinesterase inhibitor recommendations
    • Michael Valenzuela, Professor of Regenerative Neuroscience, University of Sydney
    • Perminder Sachdev, Professor of Neuropsychiatry, University of New South Wales
    • Henry Brodaty, Professor of Ageing and Mental Health, University of New South Wales
    Submitted January 18, 2018
  • Reader response: Practice guideline update summary: MCI
    • Gang Wang, Neurologist, Ruijin Hospital, Shanghai Jiaotong University (Shanghai, China)
    • Hai-lun Cui, Graduate Student, Ruijin Hospital, Shanghai Jiaotong University (Shanghai, China)
    Submitted January 14, 2018
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