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Strong epidemiologic evidence supports the efficacy of physical activity for the primary prevention of stroke.1 Physical activity has a favorable effect on vascular risk factors such as hypertension, diabetes mellitus, obesity, lipid profile, and psychosocial factors, each known to affect stroke risk.1 A growing body of literature also suggests that even among individuals who have stroke, those who led a physically active lifestyle tended to have less severe strokes.2–4 Furthermore, experimental research in animal models supports the value of exercise before and after stroke as a modifier of poststroke outcome.5 The availability of national registry studies has enabled exploration of these questions in larger samples of patients with stroke.
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Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
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- © 2018 American Academy of Neurology
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