Validation of an algorithm for identifying MS cases in administrative health claims datasets
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Article Information
- Received July 20, 2018
- Accepted in final form November 24, 2018
- First Published February 15, 2019.
Article Versions
- Previous version (February 15, 2019 - 12:45).
- You are viewing the most recent version of this article.
Author Disclosures
- William J. Culpepper, PhD, MA,
- Ruth Ann Marrie, MD, PhD,
- Annette Langer-Gould, MD, PhD,
- Mitchell T. Wallin, MD, MPH,
- Jonathan D. Campbell, PhD,
- Lorene M. Nelson, PhD,
- Wendy E. Kaye, PhD,
- Laurie Wagner, MPH,
- Helen Tremlett, PhD,
- Lie H. Chen, DrPH,
- Stella Leung, MSc,
- Charity Evans, PhD,
- Shenzhen Yao, MD, MSc,
- Nicholas G. LaRocca, PhD;
- on behalf of the United States Multiple Sclerosis Prevalence Workgroup (MSPWG)
- William J. Culpepper, PhD, MA,
National MS Prevalence Work Group, National MS Society
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- Ruth Ann Marrie, MD, PhD,
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Neurology, Editorial BoardMultiple Sclerosis Journal, Editorial Board
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Received support as principal investigator from theCanadian Institutes of Health Research (2010-2019), and Research Manitoba (2014-2019).Public Health Agency of Canada,Health Sciences Centre Foundation
Waugh Family Chair in Multiple Sclerosis
Received support as principal investigator from Multiple Sclerosis Society of Canada (2009-2016) and theNational Multiple Sclerosis Society (2013-2017), and as co-principal investigator from Multiple Sclerosis Scientific Foundation (2009-2018). Received support from Consortium of Multiple Sclerosis Centers (2004-2009, 2011-2014, 2016-2017), Crohn's and Colitis Canada (2014-2019)
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- Annette Langer-Gould, MD, PhD,
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My husband currently receives grant support from the NIH, PCORI and NCI
I received grant support from the National Institutes of Health (NIH NINDS RO1) and currently an award from PCORI
I received grant and contract support from the National Multiple Sclerosis Society
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- Mitchell T. Wallin, MD, MPH,
I sit on 1 National Institutes of Health/NINDS Data Safety Monitoring Boards.
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Editorial Advisory Board: Neuroscience Jounral 2013- present
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Consultant to the Global Burden of Diseaese Network (non- profit) and PCORI
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VA Merit Review,BX2625, co-I, 2 years
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National MS Society
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- Jonathan D. Campbell, PhD,
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(1) Amgen, (2) Astellas, (3) AstraZeneca, (4) Bayer, (5) Boehringer Ingelheim, (6) Mallinckrodt, (7) Teva, (8) Research in Real Life Ltd., (9) Respiratory Effectiveness Group, (10) Institute for Clinical and Economic Review. None of the above listed relationships are directly related to the research presented in this manuscript.
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Zogenix Inc.
(1) Colorado State Medicaid, (2) National Institute of Allergy and Infectious Diseases, (3) Agency for Healthcare Research and Quality, (4) National Institutes for Health, National Heart, Lung, and Blood Institute, (5) National Cancer Institute.
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(1) National Multiple Sclerosis Society , (2) ALSAM Foundation, (3) PhRMA Foundation, (4) The Institute for Clinical and Economic Review, (5) Enterprise Community Partners, Inc.
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- Lorene M. Nelson, PhD,
(1) Neuropace
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(1) ATSDR, Centers for Disease Control travel reimbursement for consultant travel (2) National MS Society travel reimbursement for advisory board travel (3) Muscular Dystrophy Association travel reimbursement for grant review
Neuroepidemiology, Associate Editor
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Neuroepidemiology: From Principles to Practice (Oxford University Press, 2004)
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(1) Centers for Disease Control, ATSDR, grant 1R01TS000249-01, Principal Investigator, 2016-2019 (2) National Institutes of Health (NINDS), grant 4U01NS038455- 15, Co-Investigator, 2013-2022 (3) Centers for Disease Control, ATSDR, Interagency agreement, ALS Capture-Recapture Analysis, Principal Investigator, 2015-2019 (4) National Institutes of Health, SPO #131896, Site Principal Investigator, 2018-2022 (5) NIH/NCATS, grant 4UL1TR00185-01, Co-Investigator, 2013- 2018
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(1) National Multiple Sclerosis Society
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Goldberg-Segalla, expert witness, 2014-2017
- Wendy E. Kaye, PhD,
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McKing Consulting Corporation, Senior Epidemiologist, 13 years
Association for the Accreditation of Human Subjects Research Protection Programs (AAHRPP)
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At McKing I worked on studies/projects with: The National MS Society Clinical Research Pathways Critical Path Institute US Government, Department of HHS, CDC/ATSDR
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Contract with the CDC/ATSDR to maintain/operate the National ALS Biorepository 6 years
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Critical Research Pathways 1 year
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- Laurie Wagner, MPH,
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McKing Consulting Corporation, Research Associate, 7 years
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McKing Consulting Corporation Projects: 1. The National MS Society 2. US Governnment, Department of HHS, CDC/ATSDR
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1. Contract with the CDC/ATSDR to maintain and operate the National ALS Biorepostiory, 6 years.
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- Helen Tremlett, PhD,
All non-profit: ? National US surveillance system for MS. 2013-present. Invited by the US National MS Society to form an advisory group to enable the development of a national surveillance system capable of tracking the incidence and prevalence of MS. Monthly teleconferences; one face-to-face meeting: Atlanta, Georgia (March 2014) Status: Bipartisan legislation introduced to Congress - ?Advancing Research for Neurological Diseases Act, H.R. 292.?to guide the Centers for Disease Control and Prevention in tracking the incidence and prevalence of neurological diseases, including Multiple Sclerosis and Parkinson?s disease [13th-Jan-2015; http://burgess.house.gov/blog/? postid=397459]
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Helen Tremlett is the Canada Research Chair for Neuroepidemiology and Multiple Sclerosis. Current research support received from the National Multiple Sclerosis Society, the Canadian Institutes of Health Research, the Multiple Sclerosis Society of Canada and the Multiple Sclerosis Scientific Research Foundation. In addition, in the last five years, has received research support from the Multiple Sclerosis Society of Canada (Don Paty Career Development Award); the Michael Smith Foundation for Health Research (Scholar Award) and the UK MS Trust; speaker honoraria and/or travel expenses to attend CME conferences from the Consortium of MS Centres (2013, 2018), the National MS Society (2014, 2016, 2018), ECTRIMS (2013, 2014, 2015, 2016, 2017, 2018), Biogen Idec (2014), American Academy of Neurology (2013, 2014, 2015, 2016). All speaker honoraria are either declined or donated to an MS charity or to an unrestricted grant for use by HT?s research group.
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Canada Foundation for Innovation (CFI); Canadian Institutes of Health Research [#363635 (co-PI); #190898 (PI); #404791; #387503; #388480 (all as PI); #MOP-82738 (PI) and MOP- 119393 (PI) and MOP-106607 (PI)]; the US National Multiple Sclerosis Society (Operating grants: 2012-15; 2014-17), the Multiple Sclerosis Society of Canada (2015-18: EGID #2624 (PI); 2016-18: EGID #2680 (co-PI); ) the The Multiple Sclerosis Scientific and Research Foundation (2015-18 (PI)); Canada Research Chair in Neuroepidemiology and Multiple Sclerosis
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- Lie H. Chen, DrPH,
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- Stella Leung, MSc,
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- Charity Evans, PhD,
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1. Canadian Institutes of Health Research (CIHR) (#388480), Co-PI, 2018-2022 2. CIHR (#363635), PI, 2016-2019 3. Saskatchewan Health Research Foundation (#3821), PI, 2016-2019
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1. MS Society of Canada (EGID#2918), PI, 2016-2017
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- Shenzhen Yao, MD, MSc,
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- Nicholas G. LaRocca, PhD;
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- on behalf of the United States Multiple Sclerosis Prevalence Workgroup (MSPWG)
- From the Department of Veterans Affairs Post Deployment Health Services (W.J.C., M.T.W.), Multiple Sclerosis Center of Excellence; University of Maryland (W.J.C.), Baltimore; Departments of Internal Medicine and Community Health Sciences (R.A.M., S.L.), Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; Neurology Department (A.L.-G., L.H.C.), Kaiser Permanente Southern California, Los Angeles; Georgetown University School of Medicine (M.T.W.), Washington, DC; University of Colorado (J.C.), Denver; Stanford University School of Medicine (L.M.N.), CA; McKing Consulting Corp (W.E.K., L.W.), Atlanta, GA; Faculty of Medicine (Neurology) and Centre for Brain Health (H.T.), University of British Columbia, Vancouver; College of Pharmacy and Nutrition (C.E.), University of Saskatchewan; Health Quality Council (Saskatchewan) (S.Y.), Saskatoon, Canada; and National Multiple Sclerosis Society (N.G.L.), New York, NY.
- Correspondence
Dr. Culpepper William.Culpepper{at}va.gov
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