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March 26, 2019; 92 (13)

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Listen: Audio summary of highlighted articles

In Focus

  • Spotlight on the March 26 issue
    Robert A. Gross
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Editorials

  • Muscle at the junctionWhere next generation sequencing is sending us
    Nicholas E. Johnson, Russell Butterfield
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  • Does reducing blood pressure and cholesterol provide any HOPE for preventing cognitive decline and dementia?
    Christopher Chen, Craig S. Anderson
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  • High serum neurofilament light chain predicts a worse fate in early parkinsonism
    Rizwan S. Akhtar, Tomoo Mano
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  • Managing treatment fluctuations in Parkinson disease“On” again–, “off” again
    W. Steven Metzer, Filipe B. Rodrigues
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  • Teaching neurologyGuided walk in the park or solo free-climb?
    Rachel Marie E. Salas, John T. Sladky
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In Memoriam

  • Glenn A. Mackin, MD (1954–2018)
    Steven L. Lewis, James L. Bernat
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Articles

  • Open Access
    Myasthenic congenital myopathy from recessive mutations at a single residue in NaV1.4
    Nathaniel Elia, Johanna Palmio, Marisol Sampedro Castañeda, Perry B. Shieh, Marbella Quinonez, Tiina Suominen, Michael G. Hanna, Roope Männikkö, Bjarne Udd, Stephen C. Cannon
    • Abstract
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  • Muscular and extramuscular features of myositis patients with anti-U1-RNP autoantibodies
    Maria Casal-Dominguez, Iago Pinal-Fernandez, Andrea M. Corse, Julie Paik, Jemima Albayda, Livia Casciola-Rosen, Cheilonda Johnson, Sonye K. Danoff, Lisa Christopher-Stine, Eleni Tiniakou, Andrew L. Mammen
    • Abstract
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  • Genetic basis of motoric cognitive risk syndrome in the Health and Retirement Study
    Sanish Sathyan, Tao Wang, Emmeline Ayers, Joe Verghese
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  • Effects of blood pressure and lipid lowering on cognitionResults from the HOPE-3 study
    Jackie Bosch, Martin O'Donnell, Balakumar Swaminathan, Eva Marie Lonn, Mikul Sharma, Gilles Dagenais, Rafael Diaz, Kamlesh Khunti, Basil S. Lewis, Alvaro Avezum, Claes Held, Matyas Keltai, Christopher Reid, William D. Toff, Antonio Dans, Lawrence A. Leiter, Karen Sliwa, Shun Fu Lee, Janice M. Pogue, Robert Hart, Salim Yusuf, on behalf of the HOPE-3 Investigators
    • Abstract
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  • Open Access
    Effect of prolonged antibiotic treatment on cognition in patients with Lyme borreliosis
    Anneleen Berende, Hadewych J.M. ter Hofstede, Fidel J. Vos, Michiel L. Vogelaar, Henriët van Middendorp, Andrea W.M. Evers, Roy P.C. Kessels, Bart Jan Kullberg
    • Abstract
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    CME Course
  • Dysautonomia is associated with structural and functional alterations in Parkinson disease
    Seok Jong Chung, Youn Jung Bae, Suhnyoung Jun, Han Soo Yoo, Seung Woo Kim, Yang Hyun Lee, Young H. Sohn, Seung-Koo Lee, Joon-Kyung Seong, Phil Hyu Lee
    • Abstract
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  • Levodopa-induced dyskinesia is closely linked to progression of frontal dysfunction in PD
    Han Soo Yoo, Seok Jong Chung, Yang Hyun Lee, Hye Sun Lee, Byoung Seok Ye, Young H. Sohn, Phil Hyu Lee
    • Abstract
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  • Serum NFL discriminates Parkinson disease from atypical parkinsonisms
    Tainá M. Marques, Anouke van Rumund, Patrick Oeckl, H. Bea Kuiperij, Rianne A.J. Esselink, Bastiaan R. Bloem, Markus Otto, Marcel M. Verbeek
    • Abstract
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  • Open Access
    Increased dose of carbidopa with levodopa and entacapone improves “off” time in a randomized trial
    Claudia Trenkwalder, Mikko Kuoppamäki, Mikko Vahteristo, Thomas Müller, Juha Ellmén
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  • Socioeconomic status and disability progression in multiple sclerosisA multinational study
    Katharine E. Harding, Mark Wardle, Robert Carruthers, Neil Robertson, Feng Zhu, Elaine Kingwell, Helen Tremlett
    • Abstract
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  • Open Access
    Menarche, pregnancies, and breastfeeding do not modify long-term prognosis in multiple sclerosis
    María I. Zuluaga, Susana Otero-Romero, Alex Rovira, Santiago Perez-Hoyos, Georgina Arrambide, Laura Negrotto, Ingrid Galán, Jordi Río, Manuel Comabella, Carlos Nos, María Jesús Arévalo, Angela Vidal-Jordana, Joaquin Castilló, Breogán Rodríguez, Luciana Midaglia, Patricia Mulero, Raquel Mitjana, Cristina Auger, Jaume Sastre-Garriga, Xavier Montalban, Mar Tintoré
    • Abstract
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  • A novel biomarker-based prognostic score in acute ischemic strokeThe CoRisk score
    Gian Marco De Marchis, Theresa Dankowski, Inke R. König, Joachim Fladt, Felix Fluri, Henrik Gensicke, Christian Foerch, Oliver Findling, Rebekka Kurmann, Urs Fischer, Andreas Luft, Daniela Buhl, Stefan T. Engelter, Philippe A. Lyrer, Mirjam Christ-Crain, Marcel Arnold, Mira Katan
    • Abstract
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    CME Course

What's Happening

  • What's happening in Neurology® Neuroimmunology & Neuroinflammation
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AAN Special Article

  • Humanistic dimensions of professionalism in the practice of neurology
    American Academy of Neurology Ethics, Law, and Humanities Committee
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Contemporary Issues: Innovations in Education

  • Open Access
    Core curriculum guidelines for a required clinical neurology experience
    Joseph E. Safdieh, Raghav Govindarajan, Douglas J. Gelb, Yazmin Odia, Madhu Soni
    • Abstract
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NeuroImages

  • Visibly enlarged peripheral nerves in lepromatous leprosy
    Joy Zhuo Ding, Pedro Legua
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Resident & Fellow Section

  • Resident & Fellow Rounds
    John J. Millichap, Roy E. Strowd
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  • Global & Community Health: Brief in-hospital cognitive screening anticipates complex admissions and may detect dementia
    David Bissig, Charles S. DeCarli
    • Abstract
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  • Clinical Reasoning: A teenager with persistent headache
    Yang Hu, Zhouping Tang, Wenhao Zhu, Shabei Xu
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  • Teaching NeuroImages: Scleral thickening and optic disc edema from glycosaminoglycan deposition in Hunter syndrome
    Meagan D. Seay, Heather Lau, Steven L. Galetta
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  • Teaching NeuroImages: Raccoon eye in subarachnoid hemorrhage
    Marlien Aalbers, J. Marc C. van Dijk
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Patient Page

  • What is the impact of socioeconomic status on multiple sclerosis?About multiple sclerosis
    Devon S. Conway
    • Full Text
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Disputes & Debates: Editors' Choice

  • Editors' note: Disability in adults with arthrogryposis is severe, partly invisible, and varies by genotype
    Aravind Ganesh, Steven Galetta
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  • Reader response: Disability in adults with arthrogryposis is severe, partly invisible, and varies by genotype
    Bonita Sawatzky, Judith G. Hall
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  • Author response: Disability in adults with arthrogryposis is severe, partly invisible, and varies by genotype
    Shenhao Dai, Klaus Dieterich, Marie Jaeger, Bernard Wuyam, Pierre-Simon Jouk, Dominic Pérennou
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  • Editors' note: A family-based study into penetrance in facioscapulohumeral muscular dystrophy type 1
    Aravind Ganesh, Steven Galetta
    • Full Text
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  • Reader response: A family-based study into penetrance in facioscapulohumeral muscular dystrophy type 1
    Tuy Nga Brignol, J. Andoni Urtizberea
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  • Author response: A family-based study into penetrance in facioscapulohumeral muscular dystrophy type 1
    Nicol C. Voermans, Rianne J. Goselink
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