Dietary patterns during adulthood and cognitive performance in midlife
The CARDIA study
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Article Information
- Received April 13, 2018
- Accepted in final form November 28, 2018
- First Published March 6, 2019.
Article Versions
- Previous version (March 6, 2019 - 12:45).
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Author Disclosures
- Claire T. McEvoy, PhD,
- Tina Hoang, MSPH,
- Stephen Sidney, MD,
- Lyn M. Steffen, PhD,
- David R. Jacobs Jr, PhD,
- James M. Shikany, DrPH,
- John T. Wilkins, MD and
- Kristine Yaffe, MD
- Claire T. McEvoy, PhD,
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Dr McEvoy is supported by a Beeson-CARDI Fellowship from the American Federation of Aging Research. Grant Ref LP3-04
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- Tina Hoang, MSPH,
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- Stephen Sidney, MD,
All Non-Profit Entities: (1) National Forum for Heart Disease and Stroke Prevention (2) GRADE DSMB
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All Non-Profit Entities: (1) National Forum for Heart Disease and Stroke Prevention (2) GRADE DSMB
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The Permanente Medical Group, Senior Research Scientist and Director of Research Clinics. 35 years in research scientist position
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Funded as principal investigator on NHLBI Contract N01 HC-48050 12/30/83-6/30/18; Funded as principal investigator on NINDS U54NS081760 10/1/12-9/30/17; Funded as co-investigator on NINDS U54NS081760 10/1/12-9/30/17; Funded as principal investigator on 1R01HL122658 12/1/2014-11/30/2018; Funded as co-investigator on NIDDK/ GHRI R01DK092317 10/1/12-9/30/16.
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- Lyn M. Steffen, PhD,
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Current Nutrition Reports (Springer); section editor for 3 years (2014-2017)
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research grant funding: California Walnut Commission research grant funding: Dairy Management
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grant funding from NIH/NHLBI
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- David R. Jacobs Jr, PhD,
1) Scientific Advisory Board, California Walnut Commission
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Clinical Chemistry, long term, Editorial advisory board member Circulation, long term, Statistical reviewer JAHA, long term, Statistical reviewer
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Consultant, California Walnut Commission
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Multiple (usually >10) R01 grants and contracts from the National Institutes of Health
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- James M. Shikany, DrPH,
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Title: Science Dialogue Mapping of Knowledge and Knowledge Gaps Related to the Effects of Dairy Intake on Human Health Principal Investigator: David B. Allison, PhD Role: Investigator Period of funding: 06/01/2016-03/31/2018 Total costs: $251,062 Source: Dairy Management, Inc. Title: Science Dialogue Mapping of Knowledge and Knowledge Gaps Related to the Effects of Dairy Intake on Human Health Principal Investigator: David B. Allison, PhD Role: Investigator Period of funding: 06/01/2016-03/31/2018 Total costs: $251,062 Source: Dairy Management, Inc. Title: Heart Failure with Preserved EF: Female Sex Hormones and Cyclic GMP-PKG Modulation of Cardiac Disease and Metabolism Principal Investigator: Wendy Post, MD Role: Principal Investigator of UAB subcontract Period of funding: 02/01/2017-01/31/2018 Total costs: $6,155 Source American Heart Association/Johns Hopkins University (UAB Subcontract)
Title: Coronary Artery Risk Development in Young Adults ? Coordinating Center Principal Investigator: James M. Shikany, DrPH Period of funding: 07/01/2018-06/31/2023 Total costs: $13,810,098 Source: NIH (NHLBI) Title: Osteoporotic Fractures in Men (MrOS) Renewal ? Birmingham Principal Investigator: James M. Shikany, DrPH Period of funding: 08/01/2013-04/30/2019 Total costs: $2,633,235 Source: NIH (NIAMS) Title: National Transdisciplinary Collaborative Center for Research on African American Men?s Health Principal Investigator: James M. Shikany, DrPH Period of funding: 07/01/2013-06/30/2019 Total costs: $2,674,163 Source: NIH (NIMHD) Title: Molecular Markers of Early Cardiometabolic Health Transitions in the CARDIA Study Principal Investigator: Role: Principal Investigator of UAB subcontract Period of funding: 04/01/2017-02/28/2022 Total costs: $53,626 Source: NIH (NHLBI)/Harvard University (UAB subcontract) Title: Dairy Consumption, Dietary Patterns and Cardiac Phenotypes Principal Investigator: Lyn Steffen, PhD Role: Principal Investigator of UAB subcontract Period of funding: 06/01/2017-02/28/2019 Total costs: $53,555 Source: NIH (NHLBI)/University of Minnesota (UAB subcontract) Title: Caloric and Non-caloric Sweeteners and the Distribution of Adipose Tissue Principal Investigator: Lyn Steffen, PhD Role: Principal Investigator of UAB subcontract Period of funding: 01/01/2017-12/31/2018 Total costs: $46,767 Source: NIH (NHLBI)/University of Minnesota (UAB subcontract) Title: Lung Function Decline and Disease Risk from Young Adulthood to Middle Age Principal Investigator: Ravi Kalhan, MD Role: Co-Principal Investigator of UAB subcontract Period of funding: 08/01/2014-07/31/2019 Total costs: $210,683 Source: NIH (NHLBI)/Northwestern University (UAB subcontract) Title: Pregnancy-Related Risk Factors and Glucose Tolerance in Women during Midlife Principal Investigator: Erica Gunderson, PhD Role: Principal Investigator of UAB subcontract Period of funding: 08/27/2015-07/31/2019 Total costs: $221,565 Source: NIH (NHLBI)/Kaiser Permanente (UAB subcontract) Title: Determinants of Midlife & Longitudinal Change in Cognitive Function: CARDIA Study Principal Investigators: Steve Sidney, MD and Kristine Yaffe, MD Role: Principal Investigator of UAB subcontract Period of funding: 12/01/2014-11/30/2018 Total costs: $177,486 Source: NIH/Kaiser Permanente (UAB subcontract) Title: Transdisciplinary Collaborative Center (TCC) for Colorectal Cancer Research Principal Investigator: Mona N. Fouad, MD Role: Investigator Period of funding: 07/01/2016-06/30/2019 Total costs: $399,956 Source: National Academy of Sciences Title: Diabetes Research Center Principal Investigator: Timothy W. Garvey, MD Role: Investigator Period of funding: 03/01/2013-02/28/2019 Total costs: $1,076,289 Source: NIH (NIDDK) Title: Collaboration to Improve Blood Pressure in the US Black Belt ? Addressing the Triple Threat Principal Investigator: Andrea Cherrington, MD Role: Investigator Period of Funding: 09/15/2016-08/31/2020 Total costs: $8,450,038 Source: NIH (NHLBI)/Weill Cornell University (UAB subcontract) Title: Trajectory of Anti-Mullerian Hormone Decline and CVD Risk in CARDIA Women Principal Investigator: Melissa Wellons, MD Role: Principal Investigator of UAB subcontract Period of funding: 09/01/2016-08/31/2018 Total costs: $17,671 Source NIH (NHLBI)/Vanderbilt University (UAB Subcontract) Title: Trans-Omics for Precision Medicine (TOPMed) Data Coordinating Center (DCC) Principal Investigator: James M. Shikany, DrPH Period of funding: 03/01/2018-08/31/2018 Total costs: $30,000 Source: NIH/University of Washington Title: Biomarker Associations with Cerebral Structure and Function in a Young-to-Middle Age Cohort: CARDIA Brain MRI Sub-Study Principal Investigator: James M. Shikany, DrPH Period of funding: 11/01/2014-10/31/2017 Total costs: $1,163,869 Source: NIH (NHLBI) Title: The Role of Plasminogen Activator Inhibitor-1 in the Development and Progression of Obesity Principal Investigator: Sadiya Khan, MD Role: Principal Investigator of UAB subcontract Period of funding: 08/01/2015-07/31/2017 Total costs: $17,784 Source: NIH/Northwestern University (UAB subcontract) Title: Determination of Skeletal Muscle Mass by Creatine Dilution Principal Investigator: Peggy Cawthon, PhD Role: Principal Investigator of UAB subcontract Period of funding: 09/01/2013-08/31/2017 Total costs: $79,646 Source: NIH (NIAMS)/California Pacific Medical Center (UAB subcontract) Title: Reasons for Geographic and Racial Disparities in Stroke ? Myocardial Infarction Study ? 2 (REGARDS-MI-2) Role: Principal Investigator Period of funding: 04/01/2005-01/31/2017 Total costs: $3,710,904 Source: NIH (NHLBI)
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- John T. Wilkins, MD and
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NMG Biopharmaceuticals
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NHLBI LRP (Recipient) NHLBI K23 HL133601 (PI)
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- Kristine Yaffe, MD
1)DSMB for Takeda, Inc 2)DSMBs for NIH sponsored study 3)Beeson Scientific Advisory Board 4)DZNE Senate Member
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-Associate Editor, 2011-, International Review of Psychiatry -Associate Editor 2012-16, Journal of Gerontology: Medical Sciences -Editorial Board Member 2014-, Journal of Prevention of Alzheimer?s Disease - Editorial Board Member 2017-, Alzheimer?s & Dementia: Translational Research & Clinical Interventions
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1. R01 AG026720 (Multiple PI: Yaffe and Stone) NIA Change in Sleep & Cognition in Older Women 07/06-03/19 2. K24 AG031155 (PI) NIA Predictors of cognitive aging across the lifecourse 06/13-11/20 3. P50 AG023501 (PI) NIA Alzheimer?s Disease Research Centers: Data and Statistical Core 04/14-03/19 4. Director Sierra-Pacific VISN Mental Illness Research, Educational and Clinical Center Psychiatric Fellowship 10/09-09/23 5. R01 AG05407 (Multiple PI: Yaffe and Cummings) NIA Study of Osteoporotic Fractures: Successful Aging 09/11-05/18 6. PI of Dementia Research at SF VA Medical Center Sierra-Pacific VISN Mental Illness Research, Educational and Clinical Center 10/09-09/23 7. R01 MD007019 (Co-investigator, PI: Byers) NIH: National Institute on Minority Health and Health Disparities Epidemiology of Suicidal Behavior in Racially/Ethnically Diverse Older Americans 04/12-10/17 8. P30 AG044281 (Co-Investigator, PI: Covinsky) NIA UCSF Older American Independence Center 07/13-06/18 9. (Co-Investigator, PI: Cifu) Department of Defense/VA Chronic Effects of Neurotrauma Consortium (Military and Veterans Rehabilitation and Recovery from Injury Network) 07/13-09/18 10. W81XWH-14-2-0137 (PI: Yaffe) Department of Defense Blood biomarker profile of TBI-associated cognitive impairment among old & young veterans 10/14-09/18 11. W81XWH-14-2-0176 (Co-Investigator, PI: Manley) Department of Defense Traumatic Brain Injury Endpoints Development (TED) Award 10/14-09/19 12. R01 HL122658 (Multiple PI: Yaffe and Sidney) NHLBI Determinants of Midlife & Longitudinal Change in Cognitive Function 12/14-11/18 13. W81XWH-12-PHTBI-CENC (PI: Yaffe) Department of Defense/VA Epidemiology Project. Chronic Effects of Neurotrauma Consortium (Military and Veterans Rehabilitation and Recovery from Injury Network) 02/15-09/18 14. R01 AG048234 (Co-investigator, PI: Kramer) NIA Effects of Chronic Inflammation on Brain Structure and Function 04/15-01/20 15. R01 AG032289 (Co-investigator, PI: Kramer) NIA Biological predictors of brain aging trajectories 09/15-05/20 16. W81XWH-14-1-0467 (Co-investigator, PI: Sierks) Department of Defense Oligomeric Protein Variants as Biomarkers for AD and TBI Susceptibility 09/15-09/17 17. R01 AG052964 (Co-investigator, PI: Cummings) NIA Comprehensive Evaluation of Aging-Related Clinical Outcomes and Geroproteins 06/16-05/21 18. RF1 G050745 (Co-investigator, PI: Spira) NIA The ARIC study of midlife sleep and late-life brain amyloid 06/16-05/21 19. UL1 TR991872 (Director of Pilot Grants Program, PI: Grandis) National Center for Advancing Translational Sciences Clinical and Translational Science Institute 07/16-06/21 20. W81XWH-16-1-0507 (PI: Yaffe) Department of Defense Risk and Resiliency for Dementia: Comparison of Male and Female Veterans 08/16-08/19 21. RF1 AG054443 (Multiple PI: Yaffe and Zeki-Al Hazzouri) NIA Healthy Heart, Healthy Brain? A Pooled Life-course Cohort for Dementia Risk Assessment 05/17-04/21 22. R01 AG054073 (Multiple PI: Yaffe/O?Bryant/Toga) NIA Health Disparities in Alzheimer?s Disease and Mild Cognitive Impairment among Mexican Americans 09/17-05/22 23. R01 AG057508 (Multiple PI: Yaffe/Larson) NIA Systematic Multi-Domain Alzheimer?s Risk Reduction Trial 09/17-05/21 24. R01 AG058537 (Multiple PI: Yaffe/O?Bryant) NIA An Alzheimer?s Blood Test for Primary Care 6/18-5/21
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1)Doris Duke Charitable Foundation Doris Duke Fund to Retain Clinical Scientists 2) Alzheimer?s Drug Discovery Foundation Connection Between Depressive Symptoms and Dementia:When Best to Intervene?
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- From the Centre for Public Health (C.T.M.), School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Northern Ireland, UK; Global Brain Health Institute (C.T.M., K.Y.), Department of Neurology (K.Y.), and Department of Epidemiology and Biostatistics (K.Y.), University of California, San Francisco; Trinity College Dublin (C.T.M.), Ireland; Northern California Institute for Research and Education (T.H.), San Francisco; Division of Research (S.S.), Kaiser Permanente Northern California, Oakland; Division of Epidemiology and Community Health (L.M.S., D.R.J.), School of Public Health, University of Minnesota, Minneapolis; Division of Preventive Medicine (J.M.S.), School of Medicine, University of Alabama at Birmingham; Department of Preventive Medicine and Medicine (Cardiology) (J.T.W.), Northwestern University Feinberg School of Medicine, Chicago, IL; and San Francisco Veterans Affairs Medical Center (K.Y.), CA.
- Correspondence
Dr. McEvoy c.mcevoy{at}qub.ac.uk
Article usage
Cited By...
Disputes & Debates: Rapid online correspondence
- Author response: Dietary patterns during adulthood and cognitive performance in midlife: The CARDIA study
- Claire McEvoy, Assistant Professor, Queen's University Belfast
Submitted December 17, 2019 - Reader response: Dietary patterns during adulthood and cognitive performance in midlife The CARDIA study
- Mariana I. Muñoz-Garcia, PhD Student, University of Navarra
- Estefanía Toledo, Associate professor, University of Navarra
- Miguel A. Martinez-Gonzalez, Professor & Chair Preventive Medicine & Public Health, University of Navarra
Submitted April 01, 2019
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