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April 02, 2019; 92 (14) Article

NMDA receptor antagonists and pain relief

A meta-analysis of experimental trials

View ORCID ProfileTrevor Thompson, Fiona Whiter, View ORCID ProfileKaty Gallop, View ORCID ProfileNicola Veronese, View ORCID ProfileMarco Solmi, View ORCID ProfilePaul Newton, View ORCID ProfileBrendon Stubbs
First published March 6, 2019, DOI: https://doi.org/10.1212/WNL.0000000000007238
Trevor Thompson
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Fiona Whiter
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Katy Gallop
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Nicola Veronese
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Marco Solmi
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Paul Newton
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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Brendon Stubbs
From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
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NMDA receptor antagonists and pain relief
A meta-analysis of experimental trials
Trevor Thompson, Fiona Whiter, Katy Gallop, Nicola Veronese, Marco Solmi, Paul Newton, Brendon Stubbs
Neurology Apr 2019, 92 (14) e1652-e1662; DOI: 10.1212/WNL.0000000000007238

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vol. 92 no. 14 e1652-e1662
DOI: 
https://doi.org/10.1212/WNL.0000000000007238
PubMed: 
30842296

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received August 16, 2018
  • Accepted in final form December 6, 2018
  • First Published March 6, 2019.

Article Versions

  • Previous version (March 6, 2019 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2019 American Academy of Neurology

Author Disclosures

    1. Trevor Thompson, PhD,
    2. Fiona Whiter, MSc,
    3. Katy Gallop, MSc,
    4. Nicola Veronese, MD,
    5. Marco Solmi, MD,
    6. Paul Newton, PhD and
    7. Brendon Stubbs, PhD
  1. Trevor Thompson, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Fiona Whiter, MSc,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Katy Gallop, MSc,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Acaster Lloyd Consulting Ltd, 2 years

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Nicola Veronese, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. -Ageing Research Reviews: editorial board member, 2018 -Aging Clinical and Experimental Research: editorial board member, 2016 -American Journal of Therapeutics:editorial board member, 2016 -Journal of the American Medical Directors Association: editorial board member, 2018 - European Journal Of Translational Myology (Clinical Section): section editor, 2018

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Marco Solmi, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Frontiers psychiatry American Journal of therapeutics No fundindg or compensation

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Paul Newton, PhD and
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Brendon Stubbs, PhD
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Faculty of Education and Health (T.T., F.W.), University of Greenwich, London; York Health Economics Consortium (F.W.), University of York; Acaster Lloyd Consulting Ltd. (K.G.), London, UK; Neurosciences Department (N.V.), Aging Branch, National Research Council, Padova; Neuroscience Centre (M.S.), University of Padova, Italy; Department of Adult Nursing & Paramedic Science (P.N.), University of Greenwich, London; Physiotherapy Department (B.S.), South London and Maudsley NHS Foundation Trust; and Department of Psychological Medicine (B.S.), Institute of Psychiatry, Psychology and Neuroscience, King's College London, De Crespigny Park, London, UK.
  1. Correspondence
    Dr. Thompson t.thompson{at}gre.ac.uk
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