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April 30, 2019; 92 (18) Null Hypothesis

Statins and perihemorrhagic edema in patients with spontaneous intracerebral hemorrhage

View ORCID ProfileJens Witsch, Fawaz Al-Mufti, E. Sander Connolly, Sachin Agarwal, Kara Melmed, David J. Roh, Jan Claassen, Soojin Park
First published February 6, 2019, DOI: https://doi.org/10.1212/WNL.0000000000006931
Jens Witsch
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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  • ORCID record for Jens Witsch
Fawaz Al-Mufti
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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E. Sander Connolly
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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Sachin Agarwal
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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Kara Melmed
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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David J. Roh
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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Jan Claassen
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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Soojin Park
From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
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Statins and perihemorrhagic edema in patients with spontaneous intracerebral hemorrhage
Jens Witsch, Fawaz Al-Mufti, E. Sander Connolly, Sachin Agarwal, Kara Melmed, David J. Roh, Jan Claassen, Soojin Park
Neurology Apr 2019, 92 (18) e2145-e2149; DOI: 10.1212/WNL.0000000000006931

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Article Information

vol. 92 no. 18 e2145-e2149
DOI: 
https://doi.org/10.1212/WNL.0000000000006931
PubMed: 
30728307

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received July 22, 2018
  • Accepted in final form December 14, 2018
  • First Published February 6, 2019.

Article Versions

  • Previous version (February 6, 2019 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2019 American Academy of Neurology

Author Disclosures

    1. Jens Witsch, MD,
    2. Fawaz Al-Mufti, MD,
    3. E. Sander Connolly, MD,
    4. Sachin Agarwal, MD, MPH,
    5. Kara Melmed, MD,
    6. David J. Roh, MD,
    7. Jan Claassen, MD, PhD and
    8. Soojin Park, MD
  1. Jens Witsch, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. I am a member of the editorial team of Neurology: Resident & Fellow Section.

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Fawaz Al-Mufti, MD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. E. Sander Connolly, MD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Sachin Agarwal, MD, MPH,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Kara Melmed, MD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. David J. Roh, MD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Jan Claassen, MD, PhD and
  14. Scientific Advisory Boards:
    1. SAGE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Editorial board of Neurocritical Care and Annals of Neurology

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. DANA foundation Stock/Stock Options, Medical Equipment & Materials: iCE Neurosystems, 2018

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Soojin Park, MD
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. PLOS One, Academic Editor, 2018

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. National Institute of Environmental Health Sciences of the National Institutes of Health under Award Number K01ES026833.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Departments of Neurology (J.W., S.A., K.M., D.J.R., J.C., S.P.) and Neurosurgery (E.S.C.), Columbia University Medical Center, New York, NY; Department of Neurology (J.W.), Yale School of Medicine, New Haven, CT; and Departments of Neurology, Neurosurgery, and Radiology (F.A.-M.), Westchester Medical Center, New York Medical College, Valhalla.
  1. Correspondence
    Dr. Witsch jensjulianwitsch{at}gmail.com
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