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May 28, 2019; 92 (22) Article

Out-of-pocket costs are on the rise for commonly prescribed neurologic medications

View ORCID ProfileBrian C. Callaghan, Evan Reynolds, Mousumi Banerjee, Kevin A. Kerber, Lesli E. Skolarus, Brandon Magliocco, Gregory J. Esper, James F. Burke
First published May 1, 2019, DOI: https://doi.org/10.1212/WNL.0000000000007564
Brian C. Callaghan
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Evan Reynolds
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Mousumi Banerjee
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Kevin A. Kerber
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Lesli E. Skolarus
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Brandon Magliocco
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Gregory J. Esper
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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James F. Burke
From the Health Services Research Program, Department of Neurology (B.C.C., K.A.K., L.E.S., J.F.B.), and the School of Public Health (E.R., M.B.), University of Michigan; Veterans Affairs Healthcare System (B.C.C., J.F.B.), Ann Arbor, MI; American Academy of Neurology (B.M.), Minneapolis, MN; and Department of Neurology (G.J.E.), Emory University, Atlanta, GA.
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Out-of-pocket costs are on the rise for commonly prescribed neurologic medications
Brian C. Callaghan, Evan Reynolds, Mousumi Banerjee, Kevin A. Kerber, Lesli E. Skolarus, Brandon Magliocco, Gregory J. Esper, James F. Burke
Neurology May 2019, 92 (22) e2604-e2613; DOI: 10.1212/WNL.0000000000007564

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  • Out-of-pocket costs are on the rise for commonly prescribed neurologic medications - October 08, 2019
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Abstract

Objective To determine out-of-pocket costs for neurologic medications in 5 common neurologic diseases.

Methods Utilizing a large, privately insured, health care claims database from 2004 to 2016, we captured out-of-pocket medication costs for patients seen by outpatient neurologists with multiple sclerosis (MS), peripheral neuropathy, epilepsy, dementia, and Parkinson disease (PD). We compared out-of-pocket costs for those in high-deductible health plans compared to traditional plans and explored cumulative out-of-pocket costs over the first 2 years after diagnosis across conditions with high- (MS) and low/medium-cost (epilepsy) medications.

Results The population consisted of 105,355 patients with MS, 314,530 with peripheral neuropathy, 281,073 with epilepsy, 120,720 with dementia, and 90,801 with PD. MS medications had the fastest rise in monthly out-of-pocket expenses (mean [SD] $15 [$23] in 2004, $309 [$593] in 2016) with minimal differences between medications. Out-of-pocket costs for brand name medications in the other conditions also rose considerably. Patients in high-deductible health plans incurred approximately twice the monthly out-of-pocket expense as compared to those not in these plans ($661 [$964] vs $246 [$472] in MS, $40 [$94] vs $18 [$46] in epilepsy in 2016). Cumulative 2-year out-of-pocket costs rose almost linearly over time in MS ($2,238 [$3,342]) and epilepsy ($230 [$443]).

Conclusions Out-of-pocket costs for neurologic medications have increased considerably over the last 12 years, particularly for those in high-deductible health plans. Out-of-pocket costs vary widely both across and within conditions. To minimize patient financial burden, neurologists require access to precise cost information when making treatment decisions.

Glossary

ICD-9=
International Classification of Diseases–9;
ICD-10=
International Classification of Diseases–10;
MS=
multiple sclerosis;
PD=
Parkinson disease;
TCA=
tricyclic antidepressant

Footnotes

  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Patient Page page e2622

  • Received September 6, 2018.
  • Accepted in final form January 8, 2019.
  • © 2019 American Academy of Neurology
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