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February 26, 2019; 92 (9) Article

Effect of aerobic exercise on cognition in younger adults

A randomized clinical trial

Yaakov Stern, Anna MacKay-Brandt, Seonjoo Lee, Paula McKinley, Kathleen McIntyre, Qolamreza Razlighi, Emil Agarunov, Matthew Bartels, Richard P. Sloan
First published January 30, 2019, DOI: https://doi.org/10.1212/WNL.0000000000007003
Yaakov Stern
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Anna MacKay-Brandt
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Seonjoo Lee
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Paula McKinley
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Kathleen McIntyre
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Qolamreza Razlighi
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Emil Agarunov
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Matthew Bartels
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Richard P. Sloan
From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
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Effect of aerobic exercise on cognition in younger adults
A randomized clinical trial
Yaakov Stern, Anna MacKay-Brandt, Seonjoo Lee, Paula McKinley, Kathleen McIntyre, Qolamreza Razlighi, Emil Agarunov, Matthew Bartels, Richard P. Sloan
Neurology Feb 2019, 92 (9) e905-e916; DOI: 10.1212/WNL.0000000000007003

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  • Effect of aerobic exercise on cognition in younger adults - July 23, 2019
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Article Information

vol. 92 no. 9 e905-e916
DOI: 
https://doi.org/10.1212/WNL.0000000000007003
PubMed: 
30700591

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received July 4, 2018
  • Accepted in final form October 8, 2018
  • First Published January 30, 2019.

Article Versions

  • Previous version (January 30, 2019 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2019 American Academy of Neurology

Author Disclosures

    1. Yaakov Stern, PhD,
    2. Anna MacKay-Brandt, PhD,
    3. Seonjoo Lee, PhD,
    4. Paula McKinley, PhD,
    5. Kathleen McIntyre, LCSW,
    6. Qolamreza Razlighi, PhD,
    7. Emil Agarunov, BS,
    8. Matthew Bartels, MD, MPH and
    9. Richard P. Sloan, PhD
  1. Yaakov Stern, PhD,
  2. Scientific Advisory Boards:
    1. (1) Effects on a bicycling intervention on cognitive skills and cardiovascular health (BIKE). (2) Cognitive intervention to improve simple and complex walking (CREM).

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. 2014: (1) Chicago, Alzheimer's Association (MSAC), Advisory Board Meeting, Reimbursement; (2) Barcelona, Spain, International Debate on Ageing and mental health, reimbursement; (3) Chicago, AAAS, Symposium: The Science of Resilient Aging, reimbursement; (4) Washington, D.C., IOM, Workshop on Cognitive Aging, reimbursement; (5) Philadelphia, ADNI, Steering Committee Meeting, reimbursement; (6) Boston, MA, Delirium PPG SAB-Planning of 2014, Reimbursement; (7) Copenhagen, Denmark, AAIC Annual Meeting, AIC and Lilly Symposium, Honorarium; (8) Philadelphia, Eli Lilly, Honorarium; (9) Boston, Delta Quest Foundation, Honorarium; 2015: (10) Dallas, TX, Eli Lilly, Working Group Mtg, Honorarium (11) Dallas, TX, Eli Lilly Outcome Mtg, Honorarium; (12) London, UK, Boston Healthcare Associates, Inc., Alzheimer?s Advisory Bd Mtg, Honorarium; 2016: (13) Utrecht, NL, Dutch Society for Neuropsychology, Annual Conference, Honorarium (14) Seattle, WA, NAN Annual Conference, Keynote, Honorarium. (15) Manchester, UK, Axovant, NICE Meeting, Honorarium; 2017: (16) Miami, FL, Lilly, Preclinical AD Working Group, Honorarium. (17) New York, NY, Axovant, Steering Cte Mtg & GAS Mtg, Honorarium. (18) Carmel, CA, California Walnut Commission, SAC Mtg, Reimbursement. (19) Cleveland, OH, Alzheimer's Association Cleveland Area Chapter, Foley Lecture, Reimbursement. 2018: (20) Geneva, CH, The Center for the Interdisciplinary Study of Gerontology and Vulnerability (CIGEV), Workshop on CR, reimbursement. (21) Dallas, TX, Center for Brainhealth, Distinguished Lecture, reimbursement. (22) Baltimore, MD, Annual Meeting of Johns Hopkins ADRC, reimbursement. (23) Gramado, Brazil, Congress of Brain, Behavior and Emotions, reimbursement. (24) Washington, DC, CP Study section, honorarium and reimbursement. (25) Chicago, IL, AAIC Annual Meeting. (26) Toronto, CA, IFA 14th Global Conference on Ageing. (27) Lake Tahoe, CA, Advanced Psychometric Methods in Cognitive Aging Research conference, reimbursement

    Editorial Boards:
    1. (1) Journal of the International Neuropsychological Society, Editorial Board 2013- present, (2)Cognitive and Behavioral Neurology, Editorial Board, 2005-present, (3)Neuropsychology, Editorial Board, 2006-present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Eli Lilly, (2) AbbVie Inc. (3) Takeda Global Research & Development Center Inc. (4) Piramal Imaging SA (5) AXOVANT

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1)Piramal, (2) AXOVANT, (3) California Walnut Commission

    Research Support, Government Entities:
    1. (1) NIH/NIA, R01AG034178, PI, 2009-2013. (2) NIH/NIA, 5R01AG007370, PI, 1989-2022. (3) NIH/NIA, R01AG037212-05, Co-I, 2010-2016. (4) NIH/NIA, P50 AG08702- 25, Co-I, 1998-. (5) NIH/NIA, R01AG038465-04, PI, 2011- (6) NIH/NIA, RF1AG038465, PI, 2011-(7) NIH/NIA, R01AG033546-05, PI 2010-. (8) NIH/NIA, R01AG026158, PI, 2004-2022. (9) NIH/NINDS, R01NS070600-03, Co-I, 2010-2015. (10) NIH/NIA, R37NS029993- 21, Co-I, 2013-2015. (11) NIH/Fogarty, R01AG036469-03, Co-I, 2011-2017 17. (12) NIH, R01AG041795-01A1, Co-I, 2013-2018. (13) NIA, R01AG043463, Co-I, 2012-2018. (14) NIH/NIA, R01AG043679-01A1, Co-I, 2014-19. (15) NIH/NIA, R21AG053202, Co-I, 2016-18. (16) NICHHD, R01HD082176, Co-I, 2016-21. (17) NIH/NIA, R01AG050819, Co-I, 2016-21. (18) NIMD, 1R61MH110029, Co-I, 2016-18 (19) CWC-CU,15-3273, Co-I, 2015- 17. (19) NIA/NIA, P50AG008702-25, 1997-2020. (20) NIH/NIA 1R24AG061421-01, PI, 2018-2021. (21) HRS-18-586069C, Co-I, 2018-2019. (22) NICHHD R01HD082176, Co-I, 2016-2021. (23) NIH, R01AG057962, Co-I, 2018-2023. (24) NIH/NIA P50AG008702-25, Co-I, 1997-2020. (25) NIH/NINDS, R01 NS029993, Co-I, 2015-2020. (26) NIA, 1R56AG057202-01, Co-I, 2017-2018. (27) NIH, R01 HL139489, Co-I, 2017-2021. (28) NIH, R01AG055422, Co-I, 2017-2022. (29)

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License fee payments, Technology or Inventions:
    1. (1) The Dependence Scale measures is licensed for use by commercial entities by Columbia University, and I receive funds from these licenses.

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Anna MacKay-Brandt, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Seonjoo Lee, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Paula McKinley, PhD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) Salary support from grant that funded the study reported in this paper: NIH/NIA Grant: 5 R01 AG033546-05; My role: co-investigator; (PIs: Stern/Sloan); 2010-2016

    Research Support, Academic Entities:
    1. (1) 2016-2017: was employed and salary supported full-time by Montefiore Medical Center; Support by PCORI contract #HPC-1503-28122 (PI: Litwin). My Role: project director. Work was unrelated to the study reported in this paper.

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Kathleen McIntyre, LCSW,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Qolamreza Razlighi, PhD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Emil Agarunov, BS,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Matthew Bartels, MD, MPH and
  16. Scientific Advisory Boards:
    1. 1) NIH trial DSMB for a study of exercise and Pulmonary Hypertension. 20 Medical Advisory Board for EHE Medical, NY, NY - advice on exercise physiology and wellness.

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. LIH Healthcare , Beijing China. For medical consulting, Payment for travel to China - paid to my department and institution.

    Editorial Boards:
    1. PM&R journal, Associate Editor 2007 to present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Grant Support: Improving Cognition via Exercise in Schizophrenia. R01 MH 110623 (Kimhy, David PI) Co-Investigator, (10% support) 9/1/17-8/30/22

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. Everest Foundation Support: Evaluation of improvements in Back Pain and Knee Pain with a Biomechanical Device to Alter Gait Mechanics. 1/2016-12/2018. Total $300,000, $100,000 per year. Everest Foundation Support: 3D Printing for Prosthetics and Orthotics in 3rd world and 1st World Settings. 1/2016-12/2018. Total $300,000, $100,000 per year.

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. Richard P. Sloan, PhD
  18. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIA, R01 AG058417, PI, 2018-2023 DOD, W81XWH 14-1-0236, PI, 2014-2016

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Cognitive Neuroscience Division, Department of Neurology and Taub Institute (Y.S., A.M.-B., Q.R., E.A.), Department of Biostatistics (S.L.), and Department of Psychiatry, Division of Behavioral Medicine (P.M., K.M., R.P.S.), Columbia University, New York; Division of Clinical Research (A.M.-B.), Nathan Kline Institute for Psychiatric Research, Orangeburg; Division of Biostatistics (S.L.), New York State Psychiatric Institute; and Cardiopulmonary Rehabilitation and the Human Performance Laboratory (M.B.), Columbia Presbyterian Medical Center, New York, NY.
  1. Correspondence
    Dr. Stern ys11{at}columbia.edu
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