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Certain antidepressants linked to a slightly smaller risk of stroke
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. Now a new study has found certain SSRIs and other antidepressants that increase serotonin levels in the brain the most may be associated with a reduced risk of ischemic stroke when compared to antidepressants that increase serotonin levels the least. “It is not uncommon for people with depression to also have heart disease, a risk factor for stroke, so it is important to investigate whether antidepressants raise or lower the risk of stroke,” said study author Christel Renoux, MD, PhD, of McGill University in Montreal, Canada. “While studies investigating stroke risk in people who take antidepressants compared to people who do not take them have found mixed results, our study took an even closer look, investigating stroke risk in people who take antidepressants that increase serotonin levels the most compared to people who take antidepressants that increase levels the least.”
Douros A, Dell'Aniello S, Dehghan G, Boivin JF, Renoux C. Neurology 2019;93:e1010–e1020. doi.org/10.1212/WNL.0000000000008060
CME
Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis
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Postictal serotonin levels are associated with peri-ictal apnea
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- Received August 9, 2019.
- Accepted in final form August 9, 2019.
- © 2019 American Academy of Neurology
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