Notable from Our Podcast
The featured interview from the February 12 podcast highlights a Neurology® Clinical Practice article on quality-of-life outcomes in patients presenting for evaluation of CNS tumors. In the What's Trending segment, you'll hear an interview on a landmark study showing brain cells revamp their DNA, perhaps sparking Alzheimer disease.
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From the AAN Press Room
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Why do some people stop breathing after seizures?
Could a chemical produced by the brain that regulates mood, sleep and breathing also be protective in people with epilepsy? New research has found that higher levels of serotonin in the blood after a seizure are linked to a lower incidence of seizure-related breathing problems called apneas, when a person temporarily stops breathing. “Our findings show that higher levels of serotonin after a seizure are associated with less breathing dysfunction, and while we cannot make any links between serotonin levels and a risk of sudden unexplained death in epilepsy (SUDEP), our research may provide some important clues, since SUDEP has been linked in previous research to profound breathing dysfunction after generalized convulsive seizures,” said study author Samden D. Lhatoo, MD, FRCP, of McGovern Medical School at University of Texas Health Science Center in Houston, Texas, who conducted the research at Case Western Reserve University in Cleveland, OH.
Murugesan A, Sandhya Rani M.R., Vilella L, et al. Neurology; 93:e1475–e1494. doi.org/10.1212/WNL.0000000000008244
CME
Large variation in effects during 10 years of enzyme therapy in adults with Pompe disease
Page 828
Clinical and neural responses to cognitive behavioral therapy for functional tremor
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Most-Read Articles
As of February 22, 2019
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
G. McKhann, D. Drachman, M. Folstein, et al. 1984;34:939–944. doi.org/10.1212/WNL.34.7.939
Rating neurologic impairment in multiple sclerosis: An expanded disability status scale (EDSS)
J.F. Kurtzke. 1983;33:1444–1452. doi.org/10.1212/WNL.33.11.1444
Parkinsonism: onset, progression, and mortality
M.M. Hoehn and M.D. Yahr. 1967;17:427–442. doi.org/10.1212/WNL.17.5.427
Neurosurgical horizons in Parkinson's disease
C.G. Goetz, M.R. De Long, R.D. Penn, R.A.E. Bakay. 1993;43:1–7. doi.org/10.1212/WNL.43.1_Part_1.1
Autosomal dominant cerebellar phenotypes: The genotype has settled the issue
R.N. Rosenberg. 1995;45:1–5. doi.org/10.1212/WNL.45.1.1
- Received September 9, 2019.
- Accepted in final form September 5, 2019.
- © 2019 American Academy of Neurology
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