Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
  • Specialty Sites
    • COVID-19
    • Practice Current
    • Practice Buzz
    • Without Borders
    • Equity, Diversity and Inclusion
    • Innovations in Care Delivery
  • Collections
    • Topics A-Z
    • Residents & Fellows
    • Infographics
    • Patient Pages
    • Null Hypothesis
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

User menu

  • Subscribe
  • My Alerts
  • Log in

Search

  • Advanced search
Neurology
Home
The most widely read and highly cited peer-reviewed neurology journal
  • Subscribe
  • My Alerts
  • Log in
Site Logo
  • Home
  • Latest Articles
  • Current Issue
  • Past Issues
  • Residents & Fellows

Share

November 26, 2019; 93 (22) Article

Serum elaidic acid concentration and risk of dementia

The Hisayama Study

Takanori Honda, Tomoyuki Ohara, Masakazu Shinohara, Jun Hata, Ryuji Toh, Daigo Yoshida, Mao Shibata, Tatsuro Ishida, Yoichiro Hirakawa, Yasuhiro Irino, Satoko Sakata, Kazuhiro Uchida, Takanari Kitazono, Shigenobu Kanba, Ken-Ichi Hirata, Toshiharu Ninomiya
First published October 23, 2019, DOI: https://doi.org/10.1212/WNL.0000000000008464
Takanori Honda
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tomoyuki Ohara
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Masakazu Shinohara
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jun Hata
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ryuji Toh
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daigo Yoshida
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Mao Shibata
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tatsuro Ishida
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yoichiro Hirakawa
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yasuhiro Irino
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Satoko Sakata
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kazuhiro Uchida
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takanari Kitazono
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shigenobu Kanba
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ken-Ichi Hirata
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Toshiharu Ninomiya
From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Full PDF
Short Form
Citation
Serum elaidic acid concentration and risk of dementia
The Hisayama Study
Takanori Honda, Tomoyuki Ohara, Masakazu Shinohara, Jun Hata, Ryuji Toh, Daigo Yoshida, Mao Shibata, Tatsuro Ishida, Yoichiro Hirakawa, Yasuhiro Irino, Satoko Sakata, Kazuhiro Uchida, Takanari Kitazono, Shigenobu Kanba, Ken-Ichi Hirata, Toshiharu Ninomiya
Neurology Nov 2019, 93 (22) e2053-e2064; DOI: 10.1212/WNL.0000000000008464

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Permissions

Make Comment

See Comments

Downloads
320

Share

  • Article
  • Figures & Data
  • Info & Disclosures
Loading

Article Information

vol. 93 no. 22 e2053-e2064
DOI: 
https://doi.org/10.1212/WNL.0000000000008464
PubMed: 
31645469

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received November 8, 2018
  • Accepted in final form June 28, 2019
  • First Published October 23, 2019.

Article Versions

  • Previous version (October 23, 2019 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2019 American Academy of Neurology

Author Disclosures

    1. Takanori Honda, PhD,
    2. Tomoyuki Ohara, MD, PhD,
    3. Masakazu Shinohara, MD, PhD,
    4. Jun Hata, MD, PhD,
    5. Ryuji Toh, MD, PhD,
    6. Daigo Yoshida, PhD,
    7. Mao Shibata, MD, PhD,
    8. Tatsuro Ishida, MD, PhD,
    9. Yoichiro Hirakawa, MD, PhD,
    10. Yasuhiro Irino, PhD,
    11. Satoko Sakata, MD, PhD,
    12. Kazuhiro Uchida, PhD,
    13. Takanari Kitazono, MD, PhD,
    14. Shigenobu Kanba, MD, PhD,
    15. Ken-Ichi Hirata, MD, PhD and
    16. Toshiharu Ninomiya, MD, PhD
  1. Takanori Honda, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Tomoyuki Ohara, MD, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Masakazu Shinohara, MD, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Jun Hata, MD, PhD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Ryuji Toh, MD, PhD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Sysmex Corporation

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Daigo Yoshida, PhD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Mao Shibata, MD, PhD,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Tatsuro Ishida, MD, PhD,
  16. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. Yoichiro Hirakawa, MD, PhD,
  18. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  19. Yasuhiro Irino, PhD,
  20. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Sysmex Corporation

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  21. Satoko Sakata, MD, PhD,
  22. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  23. Kazuhiro Uchida, PhD,
  24. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  25. Takanari Kitazono, MD, PhD,
  26. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Daiichi Sankyo Co., Ltd. Bayer Yakuhin, Ltd.

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Daiichi Sankyo Co., Ltd. Takeda Pharmaceutical Co., Ltd. Astellas Pharma Inc. Chugai Pharaceutical Co., Ltd. MSD K.K. Nippon Behringer Ingelheim Co., Ltd.

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  27. Shigenobu Kanba, MD, PhD,
  28. Scientific Advisory Boards:
    1. Astellas

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. received honoraria for lectures from Eli Lilly, GlaxoSmithKline, Pfizer Inc, Asahi- kasei, Meiji Seika Pharma, Taisho Toyama, Janssen, Eisai, Astellas, Otsuka, Shionogi, Dainippon Sumitomo, Kyowa Hakko Kirin, Yoshitomiyakuhin, MSD, and Wyeth

    Editorial Boards:
    1. Molecular Psychiatry, Journal of Neuroscience and Psychiatry, Asian Journal of Psychiatry, Asia Pacific Journal of Psychiatry

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Pfizer Inc., GlaxoSmithKline, Astellas, Janssen, Yoshitomiyakuhin, Eli Lilly, Otsuka, Dainippon Sumitomo, Meiji Seika Pharma, Kyowa Hakko Kirin, Shionogi, Ono Pharma

    Research Support, Government Entities:
    1. Grant from Japanese Ministry of Education and of Health

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  29. Ken-Ichi Hirata, MD, PhD and
  30. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  31. Toshiharu Ninomiya, MD, PhD
  32. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Departments of Epidemiology and Public Health (T.H., T.O., J.H., D.Y., M.Shibata, Y.H., S.S., T.N.), Neuropsychiatry (T.O., S.K.), Medicine and Clinical Science (J.H., Y.H., S.S., T.K.), and Psychosomatic Medicine (M.Shibata), and Center for Cohort Studies (J.H., M.Shibata, S.S., T.K., T.N.), Graduate School of Medical Sciences, Kyushu University, Fukuoka; Divisions of Epidemiology (M.Shinohara), Evidence-Based Laboratory Medicine (R.T., Y.I.), and Cardiovascular Medicine (T.I., K.-I.H.), and Integrated Center for Mass Spectrometry (M.Shinohara., Y.I.), Kobe University Graduate School of Medicine, Hyogo; and Department of Health Promotion (K.U.), School of Health and Nutrition Sciences, Nakamura-Gakuen University, Fukuoka, Japan.
  1. Correspondence
    Dr. Ninomiya nino{at}eph.med.kyushu-u.ac.jp
View Full Text

Article usage

Article usage: October 2019 to March 2021

AbstractFullPdfSource
Oct 2019602060115Highwire
Nov 2019691465110Highwire
Dec 201916692846Highwire
Jan 202010221411Highwire
Feb 202078766Highwire
Mar 202072631Highwire
Apr 202057041Highwire
May 202063352Highwire
Jun 2020416132Highwire
Jul 202040623Highwire
Aug 202042033Highwire
Sep 202027874Highwire
Oct 202038663Highwire
Nov 202032332Highwire
Dec 202039121Highwire
Jan 202157551Highwire
Feb 202138735Highwire
Mar 202133614Highwire

Cited By...

  • 1 Citations
  • Google Scholar

Disputes & Debates: Rapid online correspondence

No comments have been published for this article.
Comment

NOTE: All authors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.

  • Stay timely. Submit only on articles published within 6 months of issue date.
  • Do not be redundant. Read any comments already posted on the article prior to submission.
  • 200 words maximum.
  • 5 references maximum. Reference 1 must be the article on which you are commenting.
  • 5 authors maximum. Exception: replies can include all original authors of the article.
  • Submitted comments are subject to editing and editor review prior to posting.

More guidelines and information on Disputes & Debates

Compose Comment

More information about text formats

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
Author Information
NOTE: The first author must also be the corresponding author of the comment.
First or given name, e.g. 'Peter'.
Your last, or family, name, e.g. 'MacMoody'.
Your email address, e.g. higgs-boson@gmail.com
Your role and/or occupation, e.g. 'Orthopedic Surgeon'.
Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.
Publishing Agreement
NOTE: All authors, besides the first/corresponding author, must complete a separate Disputes & Debates Submission Form and provide via email to the editorial office before comments can be posted.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Vertical Tabs

You May Also be Interested in

Back to top
  • Article
    • Abstract
    • Glossary
    • Methods
    • Results
    • Discussion
    • Study funding
    • Disclosure
    • Acknowledgment
    • Appendix Authors
    • Footnotes
    • References
  • Figures & Data
  • Info & Disclosures
Advertisement

Related Articles

  • No related articles found.

Topics Discussed

  • All Cognitive Disorders/Dementia
  • Alzheimer's disease
  • Cohort studies
  • Vascular dementia
  • Risk factors in epidemiology

Alert Me

  • Alert me when eletters are published
Neurology: 96 (15)

Articles

  • Ahead of Print
  • Current Issue
  • Past Issues
  • Popular Articles
  • Translations

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Activate a Subscription
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

© 2021 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise