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March 17, 2020; 94 (11) Article

Posttraumatic vs nontraumatic headaches

A phenotypic analysis in a military population

Andrea Metti, View ORCID ProfileKaren Schwab, Alan Finkel, Renee Pazdan, Lisa Brenner, Wesley Cole, Heidi Terrio, Ann I. Scher
First published January 10, 2020, DOI: https://doi.org/10.1212/WNL.0000000000008935
Andrea Metti
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Karen Schwab
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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  • ORCID record for Karen Schwab
Alan Finkel
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Renee Pazdan
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Lisa Brenner
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Wesley Cole
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Heidi Terrio
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Ann I. Scher
From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
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Posttraumatic vs nontraumatic headaches
A phenotypic analysis in a military population
Andrea Metti, Karen Schwab, Alan Finkel, Renee Pazdan, Lisa Brenner, Wesley Cole, Heidi Terrio, Ann I. Scher
Neurology Mar 2020, 94 (11) e1137-e1146; DOI: 10.1212/WNL.0000000000008935

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Article Information

vol. 94 no. 11 e1137-e1146
DOI: 
https://doi.org/10.1212/WNL.0000000000008935
PubMed: 
31924681

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received March 8, 2019
  • Accepted in final form September 12, 2019
  • First Published January 10, 2020.

Article Versions

  • Previous version (January 10, 2020 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2020 American Academy of Neurology

Author Disclosures

    1. Andrea Metti, PhD,
    2. Karen Schwab, PhD,
    3. Alan Finkel, MD,
    4. Renee Pazdan, MD,
    5. Lisa Brenner, PhD,
    6. Wesley Cole, PhD,
    7. Heidi Terrio, MD and
    8. Ann I. Scher, PhD
  1. Andrea Metti, PhD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Andrea Metti is currently employed as a contractor at Syneos Health.

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Karen Schwab, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Congressionally Directed Medical Research Program Grant #W81XWH-08-2-0105 (already cited in the manuscript) supported the data collection, quality control, and initial analysis of the study data.

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Alan Finkel, MD,
  6. Scientific Advisory Boards:
    1. (1)Allergan Pharmaceuticals

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1)Allergan Pharmaceuticals, funding for travel to advisory board

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. (1) Allergan Pharmaceuticals

    Other activities:
    1. (1)Carolina Headache Foundation 501(C)3; President and CEO (volunteer)

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1)Defense and Veterans Brain Injury Center,salary support, 2010 - present

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Renee Pazdan, MD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. AAN - funding for travel (in kind) as conference speaker, committee member, and participant in leadership development program

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Lisa Brenner, PhD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Non-Profit - International Association for Suicide Research

    Editorial Boards:
    1. Journal of Head Trauma Rehabilitation - Associate Editor 2015 to Present

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. Private Practice - Psychology

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. I have many grants that have been funded by the VA/DoD etc. All monies go to the University of Colorado or the Department of Veterans Affairs - none of them are directly paid to me

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. National Hockey League - 2015 to Present

  11. Wesley Cole, PhD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. Brain Injury Association of North Carolina (BIANC) Board of Directors, non-profit entity, volunteer activity involved in actions and decisions requiring Board involvement for BIANC

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. 1) Congressionally Director Medical Research Programs, Collaborator, FY19 2) Congressionally Director Medical Research Programs, AI, FY19

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Heidi Terrio, MD and
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Ann I. Scher, PhD
  16. Scientific Advisory Boards:
    1. (1) Commercial entity: Allergan, Inc

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. (1) Associate editor Cephalalgia (2) Associate editor Pain Medicine

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Commercial entity: Allergan, Inc

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) Eli Lilly

    Research Support, Government Entities:
    1. (1) Defense Medical Research and Development Program, PI, 2011-14 (2) Center for Neuroscience and Regenerative Medicine, PI, 2012-14 (3) Center for Neuroscience and Regenerative Medicine, PI, 2011-13 (4) Military Clinical Neuroscience Center of Excellence, PI, 2015-17 (5) USAMRMC, Co-PI, 2016-18

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Metti Consulting Company (A.M.), Pittsburgh, PA; Defense and Veterans Brain Injury Center (K.S., A.F., R.P.), Silver Spring, MD; 9Line, LLC (K.S.), Tampa, FL; Carolina Headache Institute (A.F.), Durham, NC; Departments of Physical Medicine and Rehabilitation, Psychiatry, and Neurology (L.B.), Anschutz Medical Campus, University of Colorado Aurora; Marcus Institute for Brain Health (L.B.), Aurora; VHA Rocky Mountain Mental Illness Research Education and Clinical Center (L.B.), Denver, CO; Womack Army Medical Center (A.F., W.C.), Fort Bragg, NC; Evans Army Community Hospital (H.T.), Colorado Springs, CO; and Uniformed Services University of the Health Sciences (A.I.S.), Bethesda MD.
  1. Correspondence
    Dr. Scher ann.scher{at}usuhs.edu
View Full Text

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  • Reader response: Posttraumatic vs nontraumatic headaches: A phenotypic analysis in a military population
    • Vinod K. Gupta, Physician-Medical Director, Migraine-Headache Institution (New Delhi, India)
    Submitted January 11, 2020
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