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June 16, 2020; 94 (24) Resident & Fellow Section

Pearls and Oy-sters: Vitamin B6 deficiency presenting with new-onset epilepsy and status epilepticus in a patient with Parkinson disease

Joseph S. Modica, Deana Bonno, Karlo J. Lizarraga
First published May 28, 2020, DOI: https://doi.org/10.1212/WNL.0000000000009647
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    Figure Scalp EEG recording examples in this patient with Parkinson disease and pyridoxine deficiency causing new-onset epilepsy and status epilepticus

    Frequent, independent, multifocal epileptiform discharges (arrows) are shown with maximal amplitudes on the (A and C) right frontal (Fp2 electrode), (A and C) left frontotemporal (FT9 electrode), (B and D) midline (Fz/Cz electrodes), and (B and D) right frontotemporal regions (FT10/F8 electrodes). EEG activity was recorded with scalp electrodes positioned according to the 10–20 international system. Signals from (A and B) average referential and (C and D) bipolar montages were recorded at a sample rate of 500 Hz, sensitivity of 7 μV/mm, high-frequency filter of 70 Hz, and low-frequency filter of 1 Hz. Panels A (average referential montage) and C (bipolar montage) correspond to the same time epoch. Panels B (average referential montage) and D (bipolar montage) correspond to the same time epoch.

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