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October 20, 2020; 95 (16) Article

Association of epileptiform abnormalities and seizures in Alzheimer disease

Alice D. Lam, View ORCID ProfileRani A. Sarkis, Kyle R. Pellerin, Jin Jing, Barbara A. Dworetzky, Daniel B. Hoch, View ORCID ProfileClaire S. Jacobs, Jong Woo Lee, Daniel S. Weisholtz, Rodrigo Zepeda, View ORCID ProfileM. Brandon Westover, Andrew J. Cole, View ORCID ProfileSydney S. Cash
First published August 6, 2020, DOI: https://doi.org/10.1212/WNL.0000000000010612
Alice D. Lam
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Rani A. Sarkis
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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  • ORCID record for Rani A. Sarkis
Kyle R. Pellerin
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Jin Jing
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Barbara A. Dworetzky
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Daniel B. Hoch
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Claire S. Jacobs
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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  • ORCID record for Claire S. Jacobs
Jong Woo Lee
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Daniel S. Weisholtz
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Rodrigo Zepeda
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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M. Brandon Westover
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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  • ORCID record for M. Brandon Westover
Andrew J. Cole
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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Sydney S. Cash
From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
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  • ORCID record for Sydney S. Cash
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Citation
Association of epileptiform abnormalities and seizures in Alzheimer disease
Alice D. Lam, Rani A. Sarkis, Kyle R. Pellerin, Jin Jing, Barbara A. Dworetzky, Daniel B. Hoch, Claire S. Jacobs, Jong Woo Lee, Daniel S. Weisholtz, Rodrigo Zepeda, M. Brandon Westover, Andrew J. Cole, Sydney S. Cash
Neurology Oct 2020, 95 (16) e2259-e2270; DOI: 10.1212/WNL.0000000000010612

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Article Information

vol. 95 no. 16 e2259-e2270
DOI: 
https://doi.org/10.1212/WNL.0000000000010612
PubMed: 
32764101

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received November 18, 2019
  • Accepted in final form May 14, 2020
  • First Published August 6, 2020.

Article Versions

  • Previous version (August 6, 2020 - 12:44).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2020 American Academy of Neurology

Author Disclosures

    1. Alice D. Lam, MD, PhD*,
    2. Rani A. Sarkis, MD, MSc*,
    3. Kyle R. Pellerin, BS,
    4. Jin Jing, PhD,
    5. Barbara A. Dworetzky, MD,
    6. Daniel B. Hoch, MD,
    7. Claire S. Jacobs, MD, PhD,
    8. Jong Woo Lee, MD, PhD,
    9. Daniel S. Weisholtz, MD,
    10. Rodrigo Zepeda, MD,
    11. M. Brandon Westover, MD, PhD,
    12. Andrew J. Cole, MD and
    13. Sydney S. Cash, MD, PhD
  1. Alice D. Lam, MD, PhD*,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. 1) American Clinical Neurophysiology Society, funding for travel (hotel) to speak at annual ACNS 2020 annual meeting

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. 1) Empatica

    Research Support, Government Entities:
    1. 1) NIH - NINDS - K23 NS101037, PI, 2018-present 2) NIH - NIA - R21 AG064413, PI, 2019-present 3) NIH - NINDS - R25 NS065743, investigator on supplement, 2014-2016

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. 1) American Academy of Neurology - Susan Spencer Award

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Rani A. Sarkis, MD, MSc*,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Serves on the editorial board of Epilepsy and Behavior.

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. EEG reading for Digitrace

    Clinical procedures or imaging studies:
    1. 1- Brigham and Woman's Hospital, EEG reading, 30% effort

    Research Support, Commercial Entities:
    1. 1- UCB 2- Empatica 3- Biogen

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. 1- American Epilepsy Society

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Kyle R. Pellerin, BS,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Jin Jing, PhD,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Barbara A. Dworetzky, MD,
  10. Scientific Advisory Boards:
    1. Nonprofit research trial: Chair,DSMB for the The NIH study entitled The established status Epilepticus treatment trial (ESETT) that recently closed.

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. non Profit: role as member of the Annals of Neurology Journal and ATN oversight committee, one hotel night paid for at last ANA meeting

    Editorial Boards:
    1. Epilepsy Currents, just completed 4 years on editorial board

    Patents:
    1. NONE

    Publishing Royalties:
    1. I get a very small amount of royalties from Oxford University Press for my book entitled: Psychogenic Nonepileptic Seizures: Toward the Integration of Care, 2017

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Digitrace, Consultant, eeg interpretation, commercial Best Doctors, Clinical Consultant, commercial

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. Nonprofit, Professional advisory board for the epilepsy foundation of New England Board of Directors, American Epilepsy Society

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. site PI, the padsevonil trials, parexel/UCB

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Daniel B. Hoch, MD,
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Claire S. Jacobs, MD, PhD,
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. Dr. Jacobs is an inventor on two patents related to the synthesis and use of DNA binding small molecules targeted to transcription factor binding sites: United States Patent US 7,935,530 B2. 2007 Nov 28; United States Patent US 9,630,950. 2017 Apr 25.

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) NIH/NINDS, R25NS065743, PI, 2017- 2019 (completed June 2019)

    Research Support, Academic Entities:
    1. (1) Massachusetts General Hospital, Department of Neurology funds

    Research Support, Foundations and Societies:
    1. (1) Bluefield Project to Cure FTD, (2) Philanthropic Support for CIC Precision Medicine

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  15. Jong Woo Lee, MD, PhD,
  16. Scientific Advisory Boards:
    1. Nonprofit Investigation of silent mesial temporal lobe hyperexcitability in Alzheimer’s Disease Grant Number: NIA R21AG064413

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Epilepsy Currents, 2016-now

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Soterya Inc.: co-founder, scientific advisor

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. (1) Advance Medical; contract work (2) DigiTrace; contract work

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIH R01 NS062092; site PI NIH U01 NS098968; site PI

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  17. Daniel S. Weisholtz, MD,
  18. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) NIMH, 1R21MH107820-01A1, co-investigator, 2018 (2) DARPA, W911NF-14-2-0045, co-investigator, 2018-2019 (3) NASA, NNX16A069A, co-investigator, 2019-2020 (4) NIH, 5R01NS062092-07, co-investigator, 2019-2020 (5) NIH, 5U01NS098968-03, co-investigator, 2019-2020

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. CVS, Expert witness for plaintiff.

  19. Rodrigo Zepeda, MD,
  20. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  21. M. Brandon Westover, MD, PhD,
  22. Scientific Advisory Boards:
    1. (1) Scientific advisor for Beacon Biosignals, Inc.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. Pocket Neurology, Lippincott Williams & Wilkins (2010). Pocket Neurology, 2nd Edition, Walters-Kluwer (2016).

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NIH (1R01NS102190, 1R01NS102574, 1R01NS107291)

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. (1) Beacon Biosignals, Inc.

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  23. Andrew J. Cole, MD and
  24. Scientific Advisory Boards:
    1. 1. Precisis AG 2. Medtronic 3. Sage Therapeutics

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Neuropace - Travel

    Editorial Boards:
    1. Associate Editor, Annals Clinical and Translational Neurology

    Patents:
    1. NONE

    Publishing Royalties:
    1. UpToDate

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Consultant to Sage Therepeutics, Precisis AG Pfizer Biogen Ovid

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Neuropace Stock/Stock Options, Medical Equipment & Materials: Precisis AG, 2013 Sage Pharmaceuticals, 2013

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  25. Sydney S. Cash, MD, PhD
  26. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. Funded as PI from NIH/NINDS R01-NS062092 Stock/Stock Options, Medical Equipment & Materials: Beacon Biosignals, 2019

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Neurology (A.D.L., K.R.P., J.J., D.B.H., C.S.J., M.B.W., A.J.C., S.S.C.), Massachusetts General Hospital; Department of Neurology (R.A.S., B.A.D., J.W.L., D.S.W.), Brigham and Women's Hospital, Boston, MA; and Department of Neurology and Neurotherapeutics (R.Z.), UT Southwestern Medical Center, Dallas, TX.
  1. Correspondence
    Dr. Lam Lam.Alice{at}mgh.harvard.edu
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