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Biomarkers May Help Us Understand Recovery Time After Concussion
A blood test may help researchers understand which people may take years to recover from concussion. The study looked at a biomarker called neurofilament light chain. Researchers found that, years later, people with a history of 3 or more concussions were more likely to have high levels of the biomarker than people who had not had a concussion. High levels of the biomarker were also associated with more severe symptoms such as post-traumatic stress disorder and depression years after the concussions occurred. “While most people with mild concussions recover completely, some never get their lives back fully because of chronic disability,” said study author Kimbra L. Kenney, MD, of the National Intrepid Center of Excellence, Walter Reed National Military Medical Center, Bethesda, MD, and a Fellow of the American Academy of Neurology. “These people may benefit greatly from a test that could predict those disabilities years ahead of time.”
Exosomal neurofilament light: A prognostic biomarker for remote symptoms after mild traumatic brain injury? doi.org/10.1212/WNL.0000000000009577
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Characterizing opioid use in a US population with migraine: Results from the CaMEO study
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Miller Fisher syndrome and polyneuritis cranialis in COVID-19
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Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
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J.F. Kurtzke. 1983;33:1444–1452. doi.org/10.1212/WNL.33.11.1444
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D. Neary, J. S. Snowden, L. Gustafson, et al. 1998;51:1546-1554. doi.org/10.1212/WNL.51.6.1546
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Diagnosis and management of concussion in sportsJames P. Kelly, Jay H. Rosenberg et al.Neurology, March 01, 1997 -
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Exosomal neurofilament lightA prognostic biomarker for remote symptoms after mild traumatic brain injury?Vivian A. Guedes, Kimbra Kenney, Pashtun Shahim et al.Neurology, May 27, 2020 -
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Summary of evidence-based guideline update: Evaluation and management of concussion in sportsReport of the Guideline Development Subcommittee of the American Academy of NeurologyChristopher C. Giza, Jeffrey S. Kutcher, Stephen Ashwal et al.Neurology, March 18, 2013 -
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