This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
In “Does Screening for Adverse Effects Improve Health Outcomes in Epilepsy? A Randomized Trial,” Franco et al. compared the Adverse Event Profile (AEP) score after 18 months between patients with uncontrolled seizures and a high initial AEP score whose physicians were notified about the AEP score and those whose physicians were not provided the score. The AEP score decreased during the study period for both groups, but there was no significant difference between adverse effects between groups. Bruzzone commented that the AEP score improvement in both groups may be related to heightened awareness of adverse events by both physicians and patients because of participation in this study. She further noted that these results demonstrate the importance for physicians and patients to be cognizant of the potential for adverse events and identify methods to address them given that these events affect quality of life. Franco and Perucca agreed that study participation could have affected the results and that screening for adverse events should be routine, as should patient and physician education about adverse events, the ways in which they affect quality of life and methods to optimize treatment regimens.
In “Does Screening for Adverse Effects Improve Health Outcomes in Epilepsy? A Randomized Trial,” Franco et al. compared the Adverse Event Profile (AEP) score after 18 months between patients with uncontrolled seizures and a high initial AEP score whose physicians were notified about the AEP score and those whose physicians were not provided the score. The AEP score decreased during the study period for both groups, but there was no significant difference between adverse effects between groups. Bruzzone commented that the AEP score improvement in both groups may be related to heightened awareness of adverse events by both physicians and patients because of participation in this study. She further noted that these results demonstrate the importance for physicians and patients to be cognizant of the potential for adverse events and identify methods to address them given that these events affect quality of life. Franco and Perucca agreed that study participation could have affected the results and that screening for adverse events should be routine, as should patient and physician education about adverse events, the ways in which they affect quality of life and methods to optimize treatment regimens.
Footnotes
Author disclosures are available upon request (journal{at}neurology.org).
- © 2021 American Academy of Neurology
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
If you are uploading a letter concerning an article:
You must have updated your disclosures within six months: http://submit.neurology.org
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
