Association of APOE4 and Clinical Variability in Alzheimer Disease With the Pattern of Tau- and Amyloid-PET
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Article Information
- Received March 23, 2020
- Accepted in final form September 11, 2020
- First Published December 1, 2020.
Article Versions
- Previous version (December 1, 2020 - 12:45).
- You are viewing the most recent version of this article.
Author Disclosures
- Renaud La Joie, PhD,
- Adrienne V. Visani, BS,
- Orit H. Lesman-Segev, MD,
- Suzanne L. Baker, PhD,
- Lauren Edwards, BS,
- Leonardo Iaccarino, PhD,
- David N. Soleimani-Meigooni, MD,
- Taylor Mellinger, BS,
- Mustafa Janabi, PhD,
- Zachary A. Miller, MD,
- David C. Perry, MD,
- Julie Pham, BA,
- Amelia Strom, BS,
- Maria Luisa Gorno-Tempini, MD, PhD,
- Howard J. Rosen, MD,
- Bruce L. Miller, MD,
- William J. Jagust, MD and
- Gil D. Rabinovici, MD
- Renaud La Joie, PhD,
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National Institute for Health (K99AG065501 2020-2022)
I was employed by a French Academic Agency (Inserm,France) until February 2015.
Alzheimer's Association (AARF-16-443577, 2016-2019)
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- Adrienne V. Visani, BS,
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- Orit H. Lesman-Segev, MD,
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- Suzanne L. Baker, PhD,
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1. Genentech
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- Lauren Edwards, BS,
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- Leonardo Iaccarino, PhD,
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- David N. Soleimani-Meigooni, MD,
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(1) Alzheimer's Association [AACSF-19-617663]
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- Taylor Mellinger, BS,
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- Mustafa Janabi, PhD,
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The study was supported by the National Institute of Health (R01 AG038791).
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- Zachary A. Miller, MD,
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(1) Issued patent: Dynamic and adjustable portable X-ray filter grid. (2) Issued extension: Dynamic and adjustable filter grids.
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(1)NIH T32 AG23481 from 2009-2012. (2)NIH R01 AG032289 from 2012-2014.(3)NIH ADRC P50AG023501 2014-2015.(4)NIH K23 AG048291 2015-present.
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- David C. Perry, MD,
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(1) NIH NIA, 1K23AG045289, PI, 2014-2019(2) NIH NIA, R01AG059794, PI, 2019-present
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(1) Larry L Hillblom Foundation
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- Julie Pham, BA,
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- Amelia Strom, BS,
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- Maria Luisa Gorno-Tempini, MD, PhD,
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--NIH/NINDS R01NS050915 (Gorno-Tempini PI), 6 years.--NIH/NIA R01 AG032306 (Rosen, PI), Senior Investigator, 6years.--NIH/NIA P01AG019724-06 (Miller, PI) 6 years--NIH/NIA 5P50AG023501-12 (Gorno-Tempini, PI), 2 years.--NIH/NIDCD K24 DC015544 (Gorno-Tempini, PI), 1 year
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John Douglas French Alzheimer’s Foundation; Alzheimer’s Association; Larry L. Hillblom Foundation; Koret Family Foundation; McBean Family Foundation; Alzheimer’s Disease Center of California; Consortium for Frontotemporal Dementia Research.
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- Howard J. Rosen, MD,
Scientific advisory board for Ionis pharmaceuticals
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National Institutes of Health, multiple grants PI, Co-IState of California
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Global Brain Health InstituteAssociation for Frontotemporal Degeneration
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- Bruce L. Miller, MD,
The Tau Consortium - Scientific AdvisorThe John Douglas French Foundation - Medical AdvisorThe Larry L. Hillblom Foundation - Medical Advisory BoardThe Consortium for Frontotemporal Dementia Research - Internal AdvisorGlobal Brain Health Institute (GBHI) Co- DirectorUniversity of Washington ADRC - External AdvisorStanford University ADRC - External AdvisorArizona Alzheimer’s Disease Center (ADC) - External AdvisorMassachusetts Alzheimer Disease Research Center – External AdvisorInternational Society of FTD - USA-President, Executive Committee
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Cambridge University PressGuilford Publications, Inc.Oxford University PressNeurocaseElsevier, Inc.Up-to-dateFrontiersALS/FTD Journal (Taylor & Francis) - Editorial BoardPublishing Royalties: (1) Behavioral Neurology of Dementia, Cambridge University Press, 2009(2) Handbook of Neurology, Elsevier Inc., 2009(3) The Human Frontal Lobes, Guilford Publications, 2008(4) Frontotemporal Dementia, Oxford University Press, 2014
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Quest Diagnostics Dementia Pathway Collaboration Research Grant
(1) NIA, P50 AG23501 PI, (2004-)(2) NIA, P01 AG19724 PI, (2002-)(3) CMS, 1C1-14-001-017996 PI, (2014-)(4) NIA, T32 AG023481, Co-PI, (2010-)
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Invention/Technology: Dementia Care Pathway (Suite of tools to improve dementia diagnosis in primary care settings)Source of Payment: Quest Diagnostics
Invention/Technology: Dementia Care Pathway (Suite of tools to improve dementia diagnosis in primary care settings)Source of Payment: Quest DiagnosticsAs of 11/26/2019: No royalty payments have been received yet, but do have contractual rights to receipt of future payments
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- William J. Jagust, MD and
Banner/Genentech DSMB 2013-2020Banner/Novartis DSMB 2014-2019
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Consultant Bioclinica Consultant, Lou Ruvo Center/Cleveland Clinic Consultant, BiogenConsultant GrifolsConsultant CuraSen
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NIH, Principal Investigator on the following grants:AG034570AG025303AG044292NIH Co-Investigator on the following grants:AG012435AG021028AG031563AG019724AG030048AG032306AG024904
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Tau Consortium (Rainwater Foundation)Alzheimer's Association
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Optoceutics
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- Gil D. Rabinovici, MD
(1) Merck - scientific advisory board(2) Axon Neurosciences - scientific advisory board(3) Eisai - scientific advisory board(4) GE Healthcare - speaking honorarium
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(1) Alzheimer's Association - speaking honorarium, fundingfor travel(2) AAN - speaking/course director honoraria(3) Merck - funding for travel(4) Rainwater Charitable Foundation - funding for travel
Associate Editor for JAMA Neurology
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(1) Avid Radiopharmaceuticals(2) GE Healthcare(3) Life Molecular Imaging(4) Eli Lilly
(1) NIH/NIA R01-AG045611, PI, 2014-2019(2) NIH/NIA P50-AG023501, co-I, 2014-2019(3) NIH/NIA R01-AG048234, co-I, 2015-2020(4) NIH/NIA R01-AG038791, co-I, 2016-2021(5) NIH/NIA R01 AG062588, co-I, 2019-2024(6) NIH/NIA, R01 AG064314, co-I, 2019-2024(7) NIH/NIA, R01 AG060477, co-I, 2019-2024(8) NIH/NIA, U01 AG057195, co-PI, 2018-2023(9) NIH/NIA, R01 AG057204, co-I, 2017-2022(10) NIH/NIA, P01 AG019724, co-I, 2017-2022(11) NIH/NIA, R01 AG032289, co-I, 2015-2020(12) NIH/NINDS, R01 NS050915, co-I, 2017-2022(13) NIH/NIA, P30 AG062422, co-I, 2019-2024(14) NIH/NINDS U19NS110456, co-I, 2019-2024
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(1) Alzheimer's Association, (2) John Douglas FrenchAlzheimer's Foundation, (3) Rainwater Charitable Foundation (4) American College of Radiology
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- From the Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences (R.L.J., A.V.V., O.H.L.-V., L.E., L.I., D.N.S.-M., T.M., Z.A.M., D.C.P., J.P., A.S., M.L.G.-T., H.J.R., B.L.M., G.D.R.), and Department of Radiology and Biomedical Imaging (G.D.R.), University of California, San Francisco; Department of Diagnostic Imaging (O.H.L.-V.), Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel; Molecular Biophysics and Integrated Bioimaging Division (S.L.B., M.J., W.J.J., G.D.R.), Lawrence Berkeley National Laboratory; and Helen Wills Neuroscience Institute (W.J.J., G.D.R.), University of California Berkeley.
- Correspondence
Dr. La Joie Renaud.lajoie{at}ucsf.edu
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