This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Primary progressive aphasia (PPA) denotes gradual deterioration of language function due to neurodegeneration. Although PPA was initially considered 1 of the 2 main clinical syndromes of frontotemporal dementia pathologies, we now know that about one-third of all PPA cases are due to underlying Alzheimer disease (AD) pathology.1 Over the past quarter-century, the main focus of PPA research has been on phenotyping and differentiating its related language disorders and on the significant clinical and pathologic heterogeneity of the syndrome. A very important but less considered aspect, however, is the remarkable preservation of another aspect of cognition, namely memory, in this condition. This is especially relevant in the case of Alzheimer-related PPA (PPA-AD), given that AD pathology is often considered synonymous with the presence of memory problems.
Footnotes
Go to Neurology.org/Nhttps://n.neurology.org/lookup/doi/10.1212/WNL.0000000000011404 for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.
See page 255
- © 2021 American Academy of Neurology
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Disputes & Debates: Rapid online correspondence
NOTE: All authors' disclosures must be entered and current in our database before comments can be posted. Enter and update disclosures at http://submit.neurology.org. Exception: replies to comments concerning an article you originally authored do not require updated disclosures.
- Stay timely. Submit only on articles published within the last 8 weeks.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- 200 words maximum.
- 5 references maximum. Reference 1 must be the article on which you are commenting.
- 5 authors maximum. Exception: replies can include all original authors of the article.
- Submitted comments are subject to editing and editor review prior to posting.