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February 16, 2021; 96 (7) Editorial

What Can Longitudinal Observational Studies of Physical Activity Teach Us About Prevention of Dementia?

Nicole L. Spartano, View ORCID ProfileLeonardo Pantoni
First published January 6, 2021, DOI: https://doi.org/10.1212/WNL.0000000000011376
Nicole L. Spartano
From the Section of Endocrinology, Diabetes, Nutrition & Weight Management (N.L.S.), Boston University School of Medicine, MA; and Luigi Sacco Department of Biomedical and Clinical Sciences (L.P.), University of Milan, Italy.
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Leonardo Pantoni
From the Section of Endocrinology, Diabetes, Nutrition & Weight Management (N.L.S.), Boston University School of Medicine, MA; and Luigi Sacco Department of Biomedical and Clinical Sciences (L.P.), University of Milan, Italy.
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What Can Longitudinal Observational Studies of Physical Activity Teach Us About Prevention of Dementia?
Nicole L. Spartano, Leonardo Pantoni
Neurology Feb 2021, 96 (7) 297-298; DOI: 10.1212/WNL.0000000000011376

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Many observational studies have linked physical activity to maintenance of brain structure and function into older age. However, results of physical activity interventions have been more inconsistent in their effects on brain health.1–3 One reason might be that intervention studies need to consider the type, dose, intensity, and timing of the prescribed physical activity. Another is that they need to target a high-risk population in order to develop a successful intervention for the prevention of cognitive decline.

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  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the editorial.

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  • © 2021 American Academy of Neurology
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