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November 30, 2021; 97 (22) Editorial

Causes and Implications of Isolated Small Fiber Neuropathy

Brian C. Callaghan, J. Robinson Singleton
First published October 27, 2021, DOI: https://doi.org/10.1212/WNL.0000000000012895
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Article Information

vol. 97 no. 22 1015-1016
DOI: 
https://doi.org/10.1212/WNL.0000000000012895
PubMed: 
34706973
Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • First Published October 27, 2021.

Article Versions

Copyright & Usage: 
© 2021 American Academy of Neurology

Author Disclosures

    1. Brian C. Callaghan, MD, MS and
    2. J. Robinson Singleton, MD
  1. Brian C. Callaghan, MD, MS and
    2. Scientific Advisory Boards:

    1. NONE

    Gifts:

    1. NONE

    Funding for travel or speaker honoraria:

    1. 1) American Academy of Neurology, travel

    Editorial Boards:

    1. Co-section editor of Innovations in Care Delivery for Neurology

    Patents:

    1. NONE

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. NONE

    Consultancies:

    1. Consultant for DynaMed

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. NIH 1R01DK115687, PI, 5 year award VA CSRD Merit CX001504, PI, 4 year award

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. American Academy of Neurology Juvenile Diabetes Research Foundation

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. Consultant for medical legal cases and Division of Injury Compensation Program

  2. J. Robinson Singleton, MD
    3. Scientific Advisory Boards:

    1. 1) Non profit entity- DSMB member for NIDDK funded TINSAL- T1D study (Rodica Busui PI at University of Michigan

    Gifts:

    1. NONE

    Funding for Travel or Speaker Honoraria:

    1. None

    Editorial Boards:

    1. NONE

    Patents:

    1. Hand held, point-of-care device to test vibration sensory threshold as a diagnostic screen for peripheral neuropathy, for use in primary care screening.

    Publishing Royalties:

    1. NONE

    Employment, Commercial Entity:

    1. University of Utah, Professor, Neurology

    Consultancies:

    1. Consultant, Reviewer; Medical Review Institute of America, Salt Lake City

    Speakers' Bureaus:

    1. NONE

    Other Activities:

    1. NONE

    Clinical Procedures or Imaging Studies:

    1. NONE

    Research Support, Commercial Entities:

    1. NONE

    Research Support, Government Entities:

    1. 2R01 DK064814-09A1(Singleton/Smith PIs)04/01/2015 ? 03/31/2021NIH/NIDDKActivity for DiAbetic PolyneuropaThy (the ADAPT Study)Randomized trial comparing standard care to integrated intervention of supervised exercise and actigraphy based sedentary behavior reduction for diabetic neuropathy, using IENFD as co-primary endpoint.Role: Co-Principal Investigator1U01 NS095388-01A1(Smith PI) 6/1/2017- 5/31/2021NIH/NINDS NeuroNEXT Topiramate for Cryptogenic Sensory Polyneuropathy (TopCSPN)Multi-site randomized, double blinded placebo controlled trial of Topiramate in sensory neuropathy associated with metabolic syndrome.Role: Co-Investigator1U01 AR070498 (Amato/Carrillo PIs)9/01/17 ? 4/30/23NIH/NINDS NeuroNEXT Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy of ManNAc in Subjects with GNE Myopathy (MaGiNE trial) NN-109Multisite DBRCT running through the NINDS Neuro-NEXT networkRole: Site Principal InvestigatorNIH/NCATS UL1-TR001067 And TL1TR001066 (Dere/Hess PIs) 3/1/2018 ? 2/28/2023 University of Utah Center for Clinical and Translational ScienceProvide support to investigators in performance of human subject studies across the spectrum of translational science.Role: Director, CCTS Clinical Trial Services Foundation, Director, TINetwork Hub Liaison Team1U10NS077305-01(Singleton PI) 8/1/2018 - 7/31/2023NIH/NINDSThe Utah Regional Center for Excellence in Neuroscience Clinical Trials (UR-NEXT)Consortium for performance of multicenter clinical trials focused on neurological disease.Role: Site Principal Investigator

    Research Support, Academic Entities:

    1. NONE

    Research Support, Foundations and Societies:

    1. Larry H Miller Foundation (Singleton PI)10/1/2018 ? 3/31/2020Sensitive diagnostic screening and exercise based intervention for Metabolic Syndrome associated Polyneuropathy (MSP) Seed grant to validate reliability of Utah Early Neuropathy Scale when performed primary care medical assistants. Role: Principal Investigator

    Stock/Stock Options/Board of Directors Compensation:

    1. NONE

    License Fee Payments, Technology or Inventions:

    1. NONE

    Royalty Payments, Technology or Inventions:

    1. NONE

    Stock/Stock Options, Research Sponsor:

    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:

    1. NONE

    Legal Proceedings:

    1. NONE

  1. From the Department of Neurology (B.C.C.), University of Michigan, Ann Arbor; and Department of Neurology (J.R.S.), University of Utah, Salt Lake City.
  1. Correspondence
    Dr. Callaghan bcallagh{at}med.umich.edu
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