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March 08, 2022; 98 (10) Resident & Fellow Section

Teaching Video NeuroImage: Inverted Radial and Wartenberg Thumb Reflex in Cervical Myelopathy

View ORCID ProfileTychicus Chen
First published December 22, 2021, DOI: https://doi.org/10.1212/WNL.0000000000013262
Tychicus Chen
From the Division of Neurology, Department of Medicine, University of British Columbia, Canada.
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Teaching Video NeuroImage: Inverted Radial and Wartenberg Thumb Reflex in Cervical Myelopathy
Tychicus Chen
Neurology Mar 2022, 98 (10) e1092-e1093; DOI: 10.1212/WNL.0000000000013262

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A 75-year-old man developed progressive right-hand weakness over 3 years. Examination revealed myelopathic hand, inverted radial reflex, and Wartenberg thumb reflex (Video 1). MRI demonstrated cervical spondylotic myelopathy (Figure). Surgical decompression stabilized symptoms.

Video 1

Inverted radial reflex: when tapping the radius, there is absent brachioradialis contraction and hyperactive finger flexion. Wartenberg thumb reflex: when the affected hand applies forceful flexion at the terminal phalanges, there is adduction, flexion, and opposition of the thumb; a normal response maintains abduction and extension of the thumb.Download Supplementary Video 1 via http://dx.doi.org/10.1212/013262_Video_1

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Figure MRI of the Cervical Spine, Sagittal (A) and Axial (B and C) Views, Demonstrating Severe Multilevel Degenerative Cervical Spondylopathy With Large Disc Osteophyte Complexes at C4-5 and C5-6 and Right-Sided Spinal Canal Narrowing (Arrows) With Cord Compression

Inverted radial (supinator) reflex is a myelopathic sign localizing to C5-6.1 Interruption of C5-6 roots and pathologic spread to C8 roots lead to absent brachioradialis contraction with finger flexion.1 Wartenberg thumb reflex (distinct from unrelated Wartenberg2 sign in ulnar neuropathy) is an early sign that may precede pyramidal weakness—when the affected hand applies forceful flexion at the terminal phalanges there is adduction, flexion and opposition of the thumb.

Study Funding

The author reports no targeted funding.

Disclosure

T. Chen reports no disclosures relevant to the manuscript. Go to Neurology.org/N for full disclosures.

Acknowledgment

The author thanks the patient for permission to publish this video.

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Footnotes

  • Go to Neurology.org/N for full disclosures.

  • Teaching slides links.lww.com/WNL/B732

  • © 2021 American Academy of Neurology

References

  1. 1.↵
    1. Estanol BV,
    2. Marin OS
    . Mechanism of the inverted supinator reflex: a clinical and neurophysiological study. J Neurol Neurosurg Psychiatry. 1976;39(9):905-908.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Wartenberg R
    . Diagnostic Tests in Neurology: A Selection for Office Use. Yearbook Publishers; 1945:228.

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