Decisions With Patients and Families Regarding Aducanumab in Alzheimer Disease, With Recommendations for Consent

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.

From the Department of Neurology (W.C.), University of California San Francisco; Department of Neurology (B.D.T.), Yale School of Medicine, New Haven, CT; School of Law (R.J.B.), University of Virginia, Charlottesville; Departments of Neurology and Neurosurgery (K.M.B.), University of Florida, Gainesville; Department of Neurology (S.C.-F.), Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso; Departments of Neurology and Pediatrics (L.G.E.), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Neurology (E.P.G.), Houston Methodist Hospital, TX; Neuroethics Canada and Division of Neurology (J.I.), University of British Columbia, Vancouver, Canada; Departments of Anesthesia & Critical Care, Pediatrics, and Neurology (M.K.), Children's Hospital of Philadelphia, Pennsylvania; Neuroscience Service Line, Inova Health System (D.G.L.), Falls Church, VA; Department of Neurology (S.M.), Duke University, Durham, NC; Departments of Neurology and Neurological Surgery (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Department of Neurology (B.J.S.), Johns Hopkins University, Baltimore, MD; and Departments of Neurology and Neurosurgery (L.P.T.), University of Washington, Seattle.