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February 01, 2022; 98 (5) Research Article

Metabolomics Signature of Patients With Narcolepsy

View ORCID ProfileYves Dauvilliers, View ORCID ProfileLucie Barateau, Benita Middleton, View ORCID ProfileDaan R. van der Veen, View ORCID ProfileDebra J. Skene
First published November 29, 2021, DOI: https://doi.org/10.1212/WNL.0000000000013128
Yves Dauvilliers
From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
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Lucie Barateau
From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
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Benita Middleton
From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
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Daan R. van der Veen
From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
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Debra J. Skene
From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
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Metabolomics Signature of Patients With Narcolepsy
Yves Dauvilliers, Lucie Barateau, Benita Middleton, Daan R. van der Veen, Debra J. Skene
Neurology Feb 2022, 98 (5) e493-e505; DOI: 10.1212/WNL.0000000000013128

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Article Information

vol. 98 no. 5 e493-e505
DOI: 
https://doi.org/10.1212/WNL.0000000000013128
PubMed: 
34845055

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Print ISSN: 
0028-3878
Online ISSN: 
1526-632X
History: 
  • Received April 12, 2021
  • Accepted in final form November 12, 2021
  • First Published November 29, 2021.

Article Versions

  • Previous version (November 29, 2021 - 12:45).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2022 American Academy of Neurology

Author Disclosures

    1. Yves Dauvilliers, MD,
    2. Lucie Barateau, MD,
    3. Benita Middleton, PhD,
    4. Daan R. van der Veen, PhD and
    5. Debra J. Skene, PhD
  1. Yves Dauvilliers, MD,
  2. Scientific Advisory Boards:
    1. Pr. Dauvilliers has consulted for UCB Pharma, JAZZ, Flamel, Theranexus, Idorsia, Takeda and Bioprojet

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Pr. Dauvilliers has consulted for UCB Pharma, JAZZ, Flamel, Theranexus, Idorsia, Takeda and Bioprojet

    Editorial Boards:
    1. Associate Editor for Frontier Neurology Section Sleep and Chronobiology

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. Pr. Dauvilliers has consulted for UCB Pharma, JAZZ, Flamel, Theranexus, Idorsia, Takeda and Bioprojet

    Speakers' Bureaus:
    1. Pr. Dauvilliers has consulted for UCB Pharma, JAZZ, Flamel, Theranexus, Idorsia, Takeda and Bioprojet

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Lucie Barateau, MD,
  4. Scientific Advisory Boards:
    1. (1) Takeda (2) Jazz

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. I received funds for travel to conferences by UCB Pharma.

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Benita Middleton, PhD,
  6. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Daan R. van der Veen, PhD and
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) EU H2020-SC1-2020-Two-Stage-RTD,

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Debra J. Skene, PhD
  10. Scientific Advisory Boards:
    1. (1) UKRI-BBSRC (UK)

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1) Peripheral Nerve Society, speaker honorarium (2) Sleep Science, speaker honorarium

    Editorial Boards:
    1. Editorial Board, Chronobiology International, 2007 – Associate Editor, Journal of Sleep Research, 2008 – Advisory Board, Sleep and Biological Rhythms, 2012 – Editorial Board, Clocks & Sleep, 2018 –

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. (1) Pepsico

    Speakers' Bureaus:
    1. NONE

    Other activities:
    1. (1) Institut Thématique Interdisciplinaire NeuroStra, on jury for staff appointment

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Neurology (D.Y., L.B.), Narcolepsy-Rare Hypersomnias, Sleep Unit, National Reference Centre for Orphan Diseases, CHU Montpellier, Université Montpellier; Institute for Neurosciences of Montpellier INM (D.Y., L.B.), Université Montpellier, INSERM, France; and Chronobiology (B.M., D.R.v.d.V., D.J.S.), Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
  1. Correspondence
    Dr. Dauvilliers y-dauvilliers{at}chu-montpellier.fr
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