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December 6, 2022; 99 (23)

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In Focus

  • Spotlight on the December 6 Issue
    José G. Merino
    • Full Text
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Editorials

  • White Matter Hyperintensity Spatial Patterns Provide Clues About Underlying DiseaseLocation Matters!
    Susanne J. van Veluw, Frederik Barkhof, Markus D. Schirmer
    • Full Text
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  • Perivascular SpacesClinically Relevant but Underappreciated
    Eric Smith
    • Full Text
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  • Thrombectomy for Acute Stroke in People With CancerHopes and Challenges
    Moira K. Kapral, Gustavo Saposnik
    • Full Text
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  • Temporal Trends in Stroke Hospitalizations, Treatment Modalities, and MortalityAre We Doing Enough?
    Tracy E. Madsen, Angela M. Malek, Warren D. Lo
    • Full Text
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  • Lysine Reduction and Cognitive Outcomes in Pyridoxine-Dependent EpilepsyA New Approach to an Old Disease
    Phillip L. Pearl, Wolfram S. Kunz
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Research Articles

  • Open Access
    Association of Data-Driven White Matter Hyperintensity Spatial Signatures With Distinct Cerebral Small Vessel Disease Etiologies
    Chia-Ling Phuah, Yasheng Chen, Jeremy F. Strain, Nirupama Yechoor, Osvaldo J. Laurido-Soto, Beau M. Ances, Jin-Moo Lee, for the Alzheimer's Disease Neuroimaging Initiative
    • Abstract
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  • Open Access
    Cognitive-Driven Activities of Daily Living Impairment as a Predictor for Dementia in Parkinson DiseaseA Longitudinal Cohort Study
    Sara Becker, Merle Bode, Kathrin Brockmann, Thomas Gasser, Katja Michaelis, Susanne Solbrig, Hans-Christoph Nuerk, Claudia Schulte, Walter Maetzler, Milan Zimmermann, Daniela Berg, Inga Liepelt-Scarfone
    • Abstract
    • Full Text
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  • Open Access
    MRI-Visible Perivascular Spaces and Risk of Incident DementiaThe Framingham Heart Study
    Jose Rafael Romero, Adlin Pinheiro, Hugo J. Aparicio, Charles S. DeCarli, Serkalem Demissie, Sudha Seshadri
    • Abstract
    • Full Text
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    CME Course
  • Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in MidlifeThe Framingham Heart Study
    Claudia L. Satizabal, Jayandra Jung Himali, Alexa S. Beiser, Vasan Ramachandran, Debora Melo van Lent, Dibya Himali, Hugo J. Aparicio, Pauline Maillard, Charles S. DeCarli, William S. Harris, Sudha Seshadri
    • Abstract
    • Full Text
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  • Investigating Outcomes Post–Endovascular Thrombectomy in Acute Stroke Patients With Cancer
    Steven D. Shapiro, Sima Vazquez, Ankita Das, Jose F. Dominguez, Haris Kamal, Ji Chong, Stephan A. Mayer, Gurmeen Kaur, Chirag Gandhi, Fawaz Al-Mufti
    • Abstract
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    CME Course
  • Open Access
    Admission Rates, Time Trends, Risk Factors, and Outcomes of Ischemic and Hemorrhagic Stroke From German Nationwide Data
    Dearbhla M. Kelly, Jannik Feld, Peter M. Rothwell, Holger Reinecke, Jeanette Koeppe
    • Abstract
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  • Tranexamic Acid After Aneurysmal Subarachnoid HemorrhagePost Hoc Analysis of the ULTRA Trial
    Maud A. Tjerkstra, René Post, Menno R. Germans, Mervyn D.I. Vergouwen, Korné Jellema, Radboud W. Koot, Nyika D. Kruyt, Peter W.A. Willems, Jasper F.C. Wolfs, Frits C. de Beer, Hans Kieft, Dharmin Nanda, Bram van der Pol, Gerwin Roks, Frank de Beer, Patricia H.A. Halkes, Loes J.A. Reichman, Paul J.A.M. Brouwers, Renske M. Van den Berg-Vos, Vincent I.H. Kwa, Taco C. van der Ree, Irene Bronner, Henri P. Bienfait, Hieronymus Boogaarts, Catharina J.M. Klijn, René van den Berg, Bert A. Coert, Janneke Horn, Charles B.L.M. Majoie, Gabriël J.E. Rinkel, Yvo B.W.M. Roos, W. Peter Vandertop, Dagmar Verbaan, on behalf of the ULTRA investigators
    • Abstract
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  • Association Between Quantitative Diffusion-Weighted Magnetic Resonance Neuroimaging and Outcome After Pediatric Cardiac Arrest
    Matthew P. Kirschen, Jeffrey I. Berman, Hongyan Liu, Minhui Ouyang, Antara Mondal, Heather Griffis, Cindee Levow, Madeline Winters, Shih-Shan Lang, Jimmy Huh, Hao Huang, Robert A. Berg, Arastoo Vossough, Alexis Topjian
    • Abstract
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  • Association Between Lysine Reduction Therapies and Cognitive Outcomes in Patients With Pyridoxine-Dependent Epilepsy
    Curtis R. Coughlin, Laura A. Tseng, Levinus A. Bok, Hans Hartmann, Emma Footitt, Pasquale Striano, Brahim M. Tabarki, Roelineke J. Lunsing, Sylvia Stockler-Ipsiroglu, Shanlea Gordon, Johan L.K. Van Hove, Jose E. Abdenur, Monica Boyer, Nicola Longo, Ashley Andrews, Mirian C.H. Janssen, Annemiek van Wegberg, Chitra Prasad, Asuri N. Prasad, Molly M. Lamb, Frits A. Wijburg, Sidney M. Gospe, Clara van Karnebeek, on behalf of the International PDE Consortium
    • Abstract
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Clinical/Scientific Notes

  • Somatic Mosaic Pathogenic Variant Gradient Detected in Trace Brain Tissue From Stereo-EEG Depth Electrodes
    Zimeng Ye, Mark F. Bennett, Andrew Neal, Joshua A. Laing, Martin K. Hunn, Thanomporn Wittayacharoenpong, Marian Todaro, Sheila K. Patel, Melanie Bahlo, Patrick Kwan, Terence J. O'Brien, Ingrid E. Scheffer, Samuel F. Berkovic, Piero Perucca, Michael S. Hildebrand
    • Abstract
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Reviews

  • Finding Common Ground on the Site of Onset of Amyotrophic Lateral Sclerosis
    Michael J. Strong, Michael Swash
    • Abstract
    • Full Text
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NeuroImages

  • Recurrent Bacterial Meningitis Caused by Transethmoidal Encephalocele
    Tian Qiu, Qian Lei, Dian He
    • Full Text
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  • Adult-Onset Adrenoleukodystrophy Presenting With Atypical Location of White Matter Lesions
    Priyanka Sehrawat, Anu Gupta, Ajay Garg, Venugopalan Vishnu, Roopa Rajan, Rohit Bhatia, Mamta Bhushan Singh, M.V. Padma Srivastava
    • Full Text
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Resident & Fellow Section

  • Child Neurology: Horner Syndrome in an Otherwise Well-Appearing Infant
    Andrew Silverman, Shannon Beres
    • Abstract
    • Full Text
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  • Clinical Reasoning: A 36-Year-Old Man With Asymmetric Muscle Weakness
    Yohei Harada, Shih-Hsiu Wang, Vern C. Juel
    • Full Text
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  • Teaching NeuroImage: Atypical Unilateral Cortical Ribboning in Anti-NMDA Receptor Encephalitis
    Alex Y. Chen, David S. Wang, Komal Sawlani
    • Full Text
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  • Teaching NeuroImage: Multifocal Single Vessel Cerebrovascular Fibromuscular Dysplasia
    Praveen Kesav, Syed Irteza Hussain, Seby John
    • Full Text
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Disputes & Debates: Editors' Choice

  • Editors' Note: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Aravind Ganesh, Steven Galetta
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  • Reader Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Yuxin Yvonne Yin, Qing Sun, Bing Yan, Di Wu, Tao Yu
    • Full Text
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  • Author Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Weili Li, Zhifeng Qi, Xunming Ji, Ke Jian Liu
    • Full Text
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  • Reader Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Umberto Pensato, Michele Romoli, Andrea Zini
    • Full Text
    • Full Text (PDF)
  • Author Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Weili Li, Zhifeng Qi, Xunming Ji, Ke Jian Liu
    • Full Text
    • Full Text (PDF)
  • Reader Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Mary Penckofer, James Siegler
    • Full Text
    • Full Text (PDF)
  • Author Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Weili Li, Zhifeng Qi, Xunming Ji, Ke Jian Liu
    • Full Text
    • Full Text (PDF)
  • Reader Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Sven Poli, Joshua Mbroh
    • Full Text
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  • Author Response: Normobaric Hyperoxia Combined With Endovascular Treatment for Patients With Acute Ischemic Stroke: A Randomized Controlled Clinical Trial
    Weili Li, Zhifeng Qi, Xunming Ji, Ke Jian Liu
    • Full Text
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