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August 16, 2022; 99 (7) Reviews

Evidence-Based, Implementable Motor Rehabilitation Guidelines for Individuals With Cerebral Palsy

View ORCID ProfileAnthony Demont, View ORCID ProfileMichel Gedda, Céline Lager, Capucine de Lattre, Yann Gary, Elisabeth Keroulle, Brigitte Feuillerat, Hervé Caudan, Zoé Sancelme, Arnaud Isapof, View ORCID ProfileElke Viehweger, Matthieu Chatelin, Marianne Hochard, Julia Boivin, Pascale Vurpillat, Nathalie Genès, Xavier de Boissezon, View ORCID ProfileAudrey Fontaine, View ORCID ProfileSylvain Brochard
First published June 24, 2022, DOI: https://doi.org/10.1212/WNL.0000000000200936
Anthony Demont
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Michel Gedda
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Céline Lager
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Capucine de Lattre
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Yann Gary
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Elisabeth Keroulle
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Brigitte Feuillerat
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Hervé Caudan
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Zoé Sancelme
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Arnaud Isapof
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Elke Viehweger
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Matthieu Chatelin
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Marianne Hochard
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Julia Boivin
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Pascale Vurpillat
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Nathalie Genès
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Xavier de Boissezon
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Audrey Fontaine
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Sylvain Brochard
From the French National Authority for Health (A.D., M.G.), Saint-Denis; University of Paris, ECEVE (A.D., M.G.), Inserm, U1123, Paris; Occupational Therapy Clinic (C. Lager), Mouans Sartoux; ESEAN-APF Pediatric Rehabilitation Center (C. de Lattre), Nantes; Bourgès Clinic (Y.G.), Castelnau-le-lez; Société d’études et de soins pour les enfants paralysés et polymalformés (E.K.), Antony; Hôpitaux de Saint-Maurice (B.F.); ISPO France (H.C.), Lyon; Physiotherapy Clinic (Z.S.), Orléans; Neuropediatrics Department (A.I.), Hôpital Armand Trousseau, CRMR Neuromuscular Pathologies, APHP, Paris, France; Orthopedic Department (E.V.), Neuro-orthopedics Unit and Movement Analysis Center, Université Bâle, Basel, Switzerland; Fondation Paralysie Cérébrale (M.C., M.H., J.B., N.G.), Paris; Association Française de Pédiatrie Ambulatoire (P.V.), Talence; Physical and Rehabilitation Medicine Department (X.B.), Neurosciences, CHU, Toulouse; ToNIC, Toulouse NeuroImaging Center (X.B.), University of Toulouse, Inserm, UPS, Toulouse; ISIR (A.F.), Sorbonne University, Paris; Physical and Medical Rehabilitation Department (S.B.), CHRU Brest; Paediatric Physical and Medical Rehabilitation Department (S.B.), Fondation ILDYS, Brest; and University of Western Brittany (S.B.), Laboratory of Medical Information Processing, Inserm U1101, Brest, France.
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Citation
Evidence-Based, Implementable Motor Rehabilitation Guidelines for Individuals With Cerebral Palsy
Anthony Demont, Michel Gedda, Céline Lager, Capucine de Lattre, Yann Gary, Elisabeth Keroulle, Brigitte Feuillerat, Hervé Caudan, Zoé Sancelme, Arnaud Isapof, Elke Viehweger, Matthieu Chatelin, Marianne Hochard, Julia Boivin, Pascale Vurpillat, Nathalie Genès, Xavier de Boissezon, Audrey Fontaine, Sylvain Brochard
Neurology Aug 2022, 99 (7) 283-297; DOI: 10.1212/WNL.0000000000200936

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Abstract

Background Cerebral palsy is a life-long condition that causes heterogeneous motor disorders. Motor rehabilitation interventions must be adapted to the topography of the symptoms, ambulatory capacity, and age of the individual. Current guidelines do not differentiate between the different profiles of individuals with cerebral palsy, which limits their implementation.

Objectives To develop evidence-based, implementable guidelines for motor rehabilitation interventions for individuals with cerebral palsy according to the age, topography of the cerebral palsy, and ambulatory capacity of the individual and to determine a level of priority for each intervention.

Methods We used a mixed methods design that combined a systematic review of the literature on available motor rehabilitation interventions with expert opinions. Based on the French National Authority for Health methodology, recommendations were graded as strong, conditional, or weak. Interventions were then prioritized by the experts according to both the evidence and their own opinions on relevance and implementability to provide a guide for clinicians. All recommendations were approved by experts who were independent from the working group.

Results Strong recommendations as first-line treatments were made for gait training, physical activities, and hand-arm bimanual intensive therapy for all children and adolescents with cerebral palsy. Moderate recommendations were made against passive joint mobilizations, muscle stretching, prolonged stretching with the limb fixed, and neurodevelopmental therapies for all children and adolescents with cerebral palsy. Strong recommendations as first-line treatments were made for gait training for all adults with cerebral palsy and moderate recommendations as moderate importance interventions for strengthening exercises and ankle-foot orthoses for motor impairment of the feet and the ankles.

Discussion These guidelines, which combine research evidence and expert opinions, could help individuals with cerebral palsy and their families to codetermine rehabilitation goals with health professionals, according to their preferences.

Glossary

CP=
cerebral palsy;
FNAH=
French National Authority for Health;
GMFCS=
Gross Motor Function Classification System;
HABIT=
hand-arm bimanual intensive therapy;
ICF=
International Classification of Functioning Disability and Health;
ILE=
including lower extremities

Footnotes

  • Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.

  • Submitted and externally peer reviewed. The handling editor was Renee Shellhaas, MD, MS.

  • Editorial, page 271

  • Received January 3, 2022.
  • Accepted in final form May 19, 2022.
  • © 2022 American Academy of Neurology
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