Table of Contents — August 16, 2022, 99 (7 Supplement 1) | Neurology

August 16, 2022; 99 (7 Supplement 1)

Introduction

Open Access
Planning for Prevention of Parkinson DiseaseNow Is the Time
Grace F. Crotty, Jessi L. Keavney, Roy N. Alcalay, Kenneth Marek, Gad A. Marshall, H. Diana Rosas, Michael A. Schwarzschild
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Who to Enroll

Open Access
Who to Enroll in Parkinson Disease Prevention Trials?The Case for Genetically At-Risk Cohorts
Kellyann Niotis, Andrew B. West, Rachel Saunders-Pullman
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Open Access
Neuroprotective Trials in REM Sleep Behavior DisorderThe Way Forward Becomes Clearer
Ronald B. Postuma
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Who to Enroll in Parkinson Disease Prevention Trials?The Case for Composite Prodromal Cohorts
Samantha A. Molsberry, Katherine C. Hughes, Michael A. Schwarzschild, Alberto Ascherio
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What Interventions to Test First

Open Access
What to Test in Parkinson Disease Prevention Trials?Repurposed, Low-Risk, and Gene-Targeted Drugs
Grace F. Crotty, Michael A. Schwarzschild
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Open Access
Lifestyle Interventions for the Prevention of Parkinson DiseaseA Recipe for Action
Jules M. Janssen Daalen, Sabine Schootemeijer, Edo Richard, Sirwan K.L. Darweesh, Bastiaan R. Bloem
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How to Measure Prevention

Open Access
Outcome Assessment in Parkinson Disease Prevention TrialsUtility of Clinical and Digital Measures
Anat Mirelman, Andrew Siderowf, Lana Chahine
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Open Access
What Is the Role of Dopamine Transporter Imaging in Parkinson Prevention Clinical Trials?
John Peter Seibyl, Phillip Kuo
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Statistical Considerations in the Design of Clinical Trials Targeting Prodromal Parkinson Disease
Eric A. Macklin, Christopher S. Coffey, Michael C. Brumm, John Peter Seibyl
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Conclusions and Next Steps

Open Access
Path to Parkinson Disease PreventionConclusion and Outlook
Daniela Berg, Grace F. Crotty, Jessi L. Keavney, Michael A. Schwarzschild, Tanya Simuni, Caroline Tanner
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