September 22, 2021
- Research ArticleOpen AccessSubjective Sleep Quality and Sleep Architecture in Patients With Migraine: A Meta-analysisEmily Charlotte Stanyer, Hannah Creeney, Alexander David Nesbitt, Philip Robert Robert Holland, Jan Hoffmann
September 20, 2021
- Research ArticleEpidemiology, Clinical Features, and Outcome in a Cohort of Adolescents With Cerebral Venous ThrombosisJulia Devianne, Nicolas Legris, Isabelle Crassard, Celine Bellesme, Yannick Bejot, Celine Guidoux, Fernando Pico, David Germanaud, Michael Obadia, Diana Rodriguez, Philippe Tuppin, Manoelle Kossorotoff, Christian Denier
- Research ArticleSystematic Analysis of Brain MRI Findings in Adaptor Protein Complex 4–Associated Hereditary Spastic ParaplegiaDarius Ebrahimi-Fakhari, Julian E Alecu, Marvin Ziegler, Gregory Geisel, Catherine Jordan, Angelica D'Amore, Rebecca C. Yeh, Shyam K. Akula, Afshin Saffari, Sanjay P Prabhu, Mustafa Sahin, Edward Yang, International AP-4-HSP Registry and Natural History Study
- Research ArticleOpen AccessStructural MRI Signatures in Genetic Presentations of the Frontotemporal Dementia-Motor Neuron Disease SpectrumEdoardo Gioele Spinelli, Alma Ghirelli, Silvia Basaia, Camilla Cividini, Nilo Riva, Elisa Canu, Veronica Castelnovo, Teuta Domi, Giuseppe Magnani, Francesca Caso, Paola Caroppo, Sara Prioni, Giacomina Rossi, Lucio Tremolizzo, Ildebrando Appollonio, Vincenzo Silani, Paola Carrera, Massimo Filippi, Federica Agosta
- Research ArticlePrestroke Disability and Outcome After Thrombectomy for Emergent Anterior Circulation Large Vessel Occlusion StrokeAdam de Havenon, Alicia Castonguay, Raul Nogueira, Thanh N. Nguyen, Joey English, Sudhakar Reddy Satti, Erol Veznedaroglu, Jeffrey L. Saver, J Mocco, Pooja Khatri, Eva Mistry, Osama O. Zaidat
September 16, 2021
- Research ArticleOpen AccessSpontaneous ARIA-like Events in Cerebral Amyloid Angiopathy–Related Inflammation: A Multicenter Prospective Longitudinal Cohort StudyLaura Antolini, Jacopo C. DiFrancesco, Marialuisa Zedde, Gianpaolo Basso, Andrea Arighi, Atsushi Shima, Annachiara Cagnin, Massimo Caulo, Roxana Carare, Andreas Charidimou, Mario Cirillo, Vincenzo Di Lazzaro, Carlo Ferrarese, Alessia Giossi, Domenico Inzitari, Michela Marcon, Roberto Marconi, Masafumi Ihara, Ricardo Nitrini, Berardino Orlandi, Alessandro Padovani, Rosario Pascarella, Francesco Perini, Giulia Perini, Maria Sessa, Elio Scarpini, Fabrizio Tagliavini, Raffaella Valenti, Juan Francisco Vázquez-Costa, Alberto Villarejo-Galende, Yuta Hagiwara, Nicole Ziliotto, Fabrizio Piazza
September 15, 2021
- Research ArticleOpen AccessColorectal Cancer Survival in Multiple Sclerosis: A Matched Cohort StudyRuth Ann Marrie, Colleen Maxwell, Alyson Mahar, Okechukwu Ekuma, Chad McClintock, Dallasl Seitz, Patti Groome
September 14, 2021
- Research ArticleOpen AccessAtrial Fibrillation, Stroke, and Silent Cerebrovascular Disease: A Population-Based MRI StudyLina Rydén, Simona Sacuiu, Hanna Wetterberg, Jenna Najar, Xinxin Guo, Silke Kern, Anna Zettergren, Sara Shams, Joana B. Pereira, Lars-Olof Wahlund, Eric Westman, Ingmar Skoog
- Research ArticleMulticenter Validation of a Deep Learning Detection Algorithm for Focal Cortical DysplasiaRavnoor Singh Gill, Hyo-Min Lee, Benoit Caldairou, Seok-Jun Hong, Carmen Barba, Francesco Deleo, Ludovico D'Incerti, Vanessa Cristina Mendes Coelho, Matteo Lenge, Mira Semmelroch, Dewi Victoria Schrader, Fabrice Bartolomei, Maxime Guye, Andreas Schulze-Bonhage, Horst Urbach, Kyoo Ho Cho, Fernando Cendes, Renzo Guerrini, Graeme Jackson, R. Edward Hogan, Neda Bernasconi, Andrea Bernasconi
- Research ArticleSafety and Efficacy of Nataluzimab as Adjunctive Therapy for People With Drug-Resistant Epilepsy: A Phase 2 StudyJacqueline A. French, Andrew J. Cole, Edward Faught, William H. Theodore, Annamaria Vezzani, Kore Liow, Jonathan J. Halford, Robert Armstrong, Jerzy P. Szaflarski, Sarah Hubbard, Jagdish Patel, Kun Chen, Wei Feng, Marco Rizzo, Jacob Elkins, Gabrielle Knafler, Kimberly A. Parkerson, OPUS Study Group
- Research ArticleEffect of Changes in MS Diagnostic Criteria Over 25 Years on Time to Treatment and Prognosis in Patients With Clinically Isolated SyndromeMar Tintore, Alvaro Cobo-Calvo, Pere Carbonell, Georgina Arrambide, Susana Otero-Romero, Jordi Río, Carmen Tur, Manuel Comabella, Carlos Nos, María Jesús Arévalo, Luciana Midaglia, Ingrid Galán, Angela Vidal-Jordana, Joaquin Castilló, Breogán Rodríguez-Acevedo, Ana Zabalza, Annalaura Salerno, Cristina Auger, Jaume Sastre-Garriga, Àlex Rovira, Xavier Montalban
- EditorialMapping Epileptogenic Tissues in MRI Negative Focal Epilepsy: Can Deep Learning Uncover Hidden Lesions?Nishant Sinha, Kathryn Adamiak Davis
September 09, 2021
- Research ArticleAssociation of Clinically Evident Eye Movement Abnormalities With Motor and Cognitive Features in Patients With Motor Neuron DisordersBarbara Poletti, Federica Solca, Laura Carelli, Alberto Diena, Eleonora Colombo, Silvia Torre, Alessio Maranzano, Lucia Greco, Federica Cozza, Andrea Lizio, Roberta Ferrucci, Floriano Girotti, Federico Verde, Claudia Morelli, Christian Lunetta, Vincenzo Silani, Nicola Ticozzi
- Research ArticleCerebral Amyloid Angiopathy Pathology and Its Association With Amyloid-β PET SignalStuart McCarter, Timothy G Lesnick, Val Lowe, Michelle M. Mielke, Eleni Constantopoulos M.H.S., Alejandro A. Rabinstein, Scott A Przybelski, Hugo Botha, David T. Jones, Vijay K Ramanan, Clifford R. Jack, Ronald C. Petersen, David Knopman, Bradley F. Boeve, Melissa E. Murray, Dennis W. Dickson, Prashanthi Vemuri, Kejal Kantarci, R. Ross Reichard, Jonathan Graff-Radford
- NeuroImagesProgressive Auditory Verbal Agnosia Secondary to Alzheimer DiseaseMarina Buciuc, Keith Anthony Josephs, David T. Jones, Jennifer L. Whitwell, Jonathan Graff-Radford
- Research ArticleBlood Brain Barrier Permeability in Patients With Reversible Cerebral Vasoconstriction Syndrome Assessed With Dynamic Contrast-Enhanced MRIChia-Hung Wu, Jiing-Feng Lirng, Hsiu-Mei Wu, Yu-Hsiang Ling, Yen-Feng Wang, Jong-Ling Fuh, Chung-Jung Lin, Kan Ling, Shuu-Jiun Wang, Shih-Pin Chen
- Research ArticlePredicting Symptom Onset in Sporadic Alzheimer Disease With Amyloid PETSuzanne Schindler, Yan Li, Virginia D. Buckles, Brian Andrew Gordon, Tammie L.S. Benzinger, Guoqiao Wang, Dean Coble, William E. Klunk, Anne M. Fagan, David Holtzman, Randall J. Bateman, John C Morris, Chengjie Xiong
- Research ArticleOpen AccessEffect of Cognitive Reserve on the Association of Vascular Brain Injury With Cognition: Analysis of the PURE and CAHHM StudiesRomella Durrani, Matthias G. Friedrich, Karleen M. Schulze, Philip Awadalla, Kumar Balasubramanian, Sandra Black, Philippe Broet, David Busseuil, Dipika Desai, Trevor Dummer, Alexander Dick, Jason Hicks, Thomas Iype, David Kelton, Anish Kirpalani, Scott A. Lear, Jonathon Leipsic, Wei Li, Cheryl R. McCreary, Alan R. Moody, Michael D. Noseworthy, Grace Parraga, Paul Poirier, Sumathy Rangarajan, Dorota Szczesniak, Andrzej Szuba, Jean-Claude Tardif, Koon Teo, MBBCH, Jennifer E. Vena, Katarzyna Zatonska, Anna Zimny, Douglas S. Lee, Salim Yusuf, Sonia S. Anand, Eric E. Smith
- Research ArticleSerum Neurofilament Light Association With Progression in Natalizumab-Treated Patients With Relapsing-Remitting Multiple SclerosisClaire Bridel, Cyra E Leurs, Zoë YGJ van Lierop, Zoé LE van Kempen, Iris Dekker, Harry AM Twaalfhoven, Bastiaan Moraal, Frederik Barkhof, Bernard MJ Uitdehaag, Joep Killestein, Charlotte E Teunissen
- Research ArticleBiomarkers for Atrial Fibrillation Detection After Stroke: Systematic Review and Meta-analysisAlan Cameron, Huen Ki Cheng, Ren-Ping Lee, Daniel Doherty, Mark Hall, Pouria Khashayar, Gregory Lip, Terence Quinn, Azmil Abdul-Rahim, Jesse Dawson
- Research ArticleClinical Correlation of Multiple Sclerosis Immunopathologic SubtypesW. Oliver Tobin, Alicja Kalinowska-Lyszczarz, Stephen D. Weigand, Yong Guo, Nirubol Tosakulwong, Joseph E E. Parisi, Imke Metz, Josa M. Frischer, Hans Lassmann, Wolfgang Brück, Linda Linbo, Claudia F. Lucchinetti
- EditorialRelationship Between Serum Neurofilament Light and Multiple Sclerosis Disability Progression: Clear as MudCarolyn Goldschmidt, Robert J. Fox
- Research Methods in NeurologyOpen AccessApplying Propensity Score Methods in Clinical Research in NeurologyPeter C. Austin, Amy Ying Xin Yu, Manav V. Vyas, Moira K. Kapral
- Research ArticleEpidemiology of Treated Epilepsy in New Zealand Children: A Focus on EthnicityShayma Ali, James Stanley, Suzanne Davis, Ngaire Keenan, Ingrid Scheffer, Lynette Grant Sadleir
- Research ArticleLong-term Risks of Persistent Ventral Spinal CSF Leaks in SIH: Superficial Siderosis and Bibrachial AmyotrophyWouter I. Schievink, Marcel Maya, Franklin Moser, Miriam Nuño
- Resident Page: Clinical ReasoningClinical Reasoning: Middle-aged Man With Progressive Gait AbnormalitiesJunyu Lin, Yanbing Hou, Huifang Shang
September 08, 2021
- Clinical/Scientific NotesSporadic Creutzfeldt-Jakob Disease in a Very Young PersonBrian Stephen Appleby, Ryan Maddox, Lawrence B. Schonberger, ignazio cali, Teresa Hammett, Mark Cohen, Ermias Belay
- Research ArticleChanges in Cortical Excitability and Parkinson Tremor After Botulinum Toxin TherapyOlivia Samotus, Robert Chen, Mandar Jog
- Research ArticleOpen AccessPerception and Use of Compensation Strategies for Gait Impairment by Persons With Parkinson DiseaseAnouk Tosserams, Lisanne Wit, Ingrid H.W.M. Sturkenboom, Maarten J. Nijkrake, Bastiaan R. Bloem, Jorik Nonnekes
September 07, 2021
- Research ArticleReflexive Eye Closure in Response to Cone and Melanopsin Stimulation: A Study of Implicit Measures of Light Sensitivity in MigraineEric A Kaiser, Harrison McAdams, Aleksandra Igdalova, Edda B Haggerty, Brett L Cucchiara, David H Brainard, Geoffrey K Aguirre
- Research ArticleOpen AccessAssociation of Elbow Flexor MRI Fat Fraction With Loss of Hand-to-Mouth Movement in Patients With Duchenne Muscular DystrophyKarin J. Naarding, Menno van der Holst, Erik W. van Zwet, Nienke M. van de Velde, Imelda J.M. de Groot, Jan J.G.M. Verschuuren, Hermien E. Kan, Erik H. Niks
- Research ArticleOpen AccessComparing Perimenstrual and Nonperimenstrual Migraine Attacks Using an e-DiaryDaphne S. van Casteren, Iris E. Verhagen, Britt W.H. van der Arend, Erik W. van Zwet, Antoinette MaassenVanDenBrink, Gisela M. Terwindt
- Research ArticleOpen AccessInfluence of Cognitive Reserve on Cognitive Trajectories: Role of Brain PathologiesXuerui Li, Ruixue Song, Xiuying Qi, Hui Xu, Wenzhe Yang, Miia Kivipelto, David A Bennett, Weili Xu
- Research ArticleAssociation Between Body Mass Index and Disability in Children With Charcot-Marie-Tooth DiseaseGabrielle A. Donlevy, Sarah P. Garnett, Kayla M.D. Cornett, Marnee J. McKay, Jennifer N. Baldwin, Rosemary R. Shy, Sabrina W. Yum, Timothy Estilow, Isabella Moroni, Maria Foscan, Emanuela Pagliano, Davide Pareyson, Matilde Laura, Trupti Bhandari, Francesco Muntoni, Mary M. Reilly, Richard S. Finkel, Janet E. Sowden, Katy J. Eichinger, David N. Herrmann, Michael E. Shy, Joshua Burns, Manoj P. Menezes
- Research ArticleDiscovery and Development of Pregabalin (Lyrica): The Role of Public FundingRachel Barenie, Jonathan Darrow, Jerry Avorn, Aaron Kesselheim
- ReviewMonogenic Epilepsies: Disease Mechanisms, Clinical Phenotypes, and Targeted TherapiesRenzo Guerrini, Simona Balestrini, Elaine C. Wirrell, Matthew C. Walker
- Research ArticleOpen AccessComparing the Clinical Utility and Diagnostic Performance of Cerebrospinal Fluid P-Tau181, P-Tau217 and P-Tau231 AssaysAntoine Leuzy, Shorena Janelidze, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Dirk Jacobs, Claudia Cicognola, Erik Stomrud, Eugeen Vanmechelen, Jeffrey L. Dage, Oskar Hansson
September 06, 2021
- EditorialOpen AccessCall for Emergency Action to Limit Global Temperature Increases, Restore Biodiversity, and Protect Health: Wealthy Nations Must Do Much More, Much FasterLukoye Atwoli, Abdullah H. Baqui, Thomas Benfield, Raffaella Bosurgi, Fiona Godlee, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Carlos Augusto Monteiro, Ian Norman, Kirsten Patrick, Nigel Praities, Marcel GM Olde Rikkert, Eric J. Rubin, Peush Sahni, Richard Smith, Nick Talley, Sue Turale, Damián Vázquez
September 02, 2021
- EditorialWords and Actions: Ensuring That an Equity, Diversity, Inclusion, and Anti-racism Pledge Promotes Meaningful ChangeIma M. Ebong, Andrew R. Spector
- EditorialLonger-Term Safety of B-Cell Therapy With Ocrelizumab in Multiple SclerosisE. Ann Yeh, Dennis Bourdette, Heinz Wiendl
- Research ArticleAn MRI-Based Machine Learning Prediction Framework to Lateralize Hippocampal Sclerosis in Patients With Temporal Lobe EpilepsyBenoit Caldairou, Niels A Foit, Carlotta Mutti, Fatemeh Fadaie, Ravnoor Gill, Hyo Min Lee, Theo Demerath, Horst Urbach, Andreas Schulze-Bonhage, Andrea Bernasconi, Neda Bernasconi
- Research ArticleOpen AccessSafety of Ocrelizumab in Patients With Relapsing and Primary Progressive Multiple SclerosisStephen L Hauser, Ludwig Kappos, Xavier Montalban, Licinio Craveiro, Cathy Chognot, Richard Hughes, Harold Koendgen, Noemi Pasquarelli, Ashish Pradhan, Kalpesh Prajapati, Jerry S. Wolinsky
- Clinical/Scientific NotesNeuropathologic Findings in a Patient With Juvenile-Onset Levodopa Responsive Parkinsonism Due to ATP13A2 MutationHsin Fen Chien, Roberta Diehl Rodriguez, Vincenzo Bonifati, Ricardo Nitrini, Carlos Augusto Pasqualucci, Ellen Gelpi, Egberto Reis Barbosa
- NeuroImagesClinical and Neuroimaging Features of Encephalocraniocutaneous LipomatosisMarianna P. M. de Moraes, Fabiano Ferreira de Abrantes, Thiago Yoshinaga Tonholo Silva, José Luiz Pedroso, Victor Hugo R. Marussi, Andrea Meneses, Orlando G. P. Barsottini
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