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Reader response: Prevalence and correlates of periodic limb movements in OSA and the effect of CPAP therapy

  • Richard Byrne, Physician, AAN
Submitted June 18, 2020

I read the article by Budhiraja et al.1 with interest. In the methods section the authors define a periodic limb movement of sleep (PLMS) as "[t]he minimum duration of a leg movement event was 0.5 seconds, the maximum duration was 10 seconds, and the minimum amplitude was an 8 μV increase in EMG voltage above resting EMG. The leg movements during a period from 0.5 seconds preceding an apnea or hypopnea event to 0.5 seconds following an apnea or hypopnea event were excluded." However, this is not the definition for PLMS; it is the definition for a limb movement (LM). Are you able to confirm that PLM index (PLMI) and limb movement index (LMI) were calculated separately, and are you able provide that data?

Disclosure

The author reports no relevant disclosures. Contact journal@neurology.org for full disclosures.

Reference

  1. Budhiraja R, Javaheri S, Pavlova MK, et al. Prevalence and correlates of periodic limb movements in OSA and the effect of CPAP therapy. Neurology 2020;94:1820–1827.

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Neurology | Print ISSN:0028-3878
Online ISSN:1526-632X

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