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November 11, 2015ArticleOpen Access

Disruption of posteromedial large-scale neural communication predicts recovery from coma

Stein Silva, Francesco de Pasquale, Corine Vuillaume, Beatrice Riu, Isabelle Loubinoux, Thomas Geeraerts, Thierry Seguin, Vincent Bounes, Olivier Fourcade, Jean-Francois Demonet, Patrice Péran
First published November 11, 2015, DOI: https://doi.org/10.1212/WNL.0000000000002196
Stein Silva
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Francesco de Pasquale
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Corine Vuillaume
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Beatrice Riu
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Isabelle Loubinoux
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Thomas Geeraerts
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Thierry Seguin
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Vincent Bounes
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Olivier Fourcade
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Jean-Francois Demonet
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Patrice Péran
From the Critical Care Unit (S.S., B.R.), Critical Care and Anaesthesiology Department (S.S., C.V., B.R., T.G., T.S., O.F.), and SAMU 31 (V.B.), University Teaching Hospital of Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9; INSERM U825 (S.S., C.V., I.L., P.P.), CHU Purpan, Place du Dr Baylac, F-31059 Toulouse Cedex 9, France; Department of Radiology (F.d.P.), Santa Lucia Foundation, Rome; ITAB (F.d.P.), Department of Neuroscience Imaging and Clinical Science, G. D'Annunzio University, Chieti, Italy; and Leenaards Memory Center (J.-F.D.), Department of Clinical Neuroscience CHUV and University of Lausanne, Switzerland.
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Chinese Translation

Neurology® data supplements are not copyedited before publication. Published editorials and translations have been copyedited.
© 2016 American Academy of Neurology.

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