May 22, 2013Article
Migraine, depression, and brain volume
The AGES-Reykjavik Study
Larus S. Gudmundsson, Ann I. Scher, Sigurdur Sigurdsson, Mirjam I. Geerlings, Jean-Sebastien Vidal, Gudny Eiriksdottir, Melissa I. Garcia, Tamara B. Harris, Olafur Kjartansson, Thor Aspelund, Mark A. van Buchem, Vilmundur Gudnason, Lenore J. Launer
First published May 22, 2013, DOI: https://doi.org/10.1212/WNL.0b013e318295d69e
Larus S. Gudmundsson
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Ann I. Scher
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Sigurdur Sigurdsson
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Mirjam I. Geerlings
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Jean-Sebastien Vidal
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Gudny Eiriksdottir
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Melissa I. Garcia
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Tamara B. Harris
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Olafur Kjartansson
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Thor Aspelund
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Mark A. van Buchem
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Vilmundur Gudnason
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
Lenore J. Launer
From the Department of Preventive Medicine and Biometrics (L.S.G., A.I.S.), Uniformed Services University of the Health Sciences; Laboratory of Epidemiology, Demography and Biometry (L.S.G., A.I.S., M.I.G., J.-S.V., M.I.G., T.B.H., L.J.L.), National Institute on Aging, Bethesda, MD; Icelandic Heart Association (S.S., G.E., O.K., T.A., V.G.), Kopavogur, Iceland; University Medical Center Utrecht (M.I.G.), Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands; Université Paris Descartes (J.-S.V.), Sorbonne Paris Cité, Paris, France; Faculty of Medicine (T.A., V.G.), University of Iceland, Reykjavik, Iceland; and Department of Radiology (M.A.v.B.), Leiden University Medical Center, Leiden, the Netherlands.
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