RT Journal Article
SR Electronic
T1 Brainstem seizures in hydranencephaly
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 1152
OP 1152
DO 10.1212/WNL.24.12.1152
VO 24
IS 12
A1 JOHN H. FERGUSON
A1 MORRIS W. LEVINSOHN
A1 IRAJ DERAKSHAN
YR 1974
UL http://n.neurology.org/content/24/12/1152.abstract
AB Article abstract A child with hydranencephaly had seizures typical for the neonatal period, including frequent clonic episodes and a paroxysmal electroencephalogram (EEG) with spikes, and at postmortem had no brain above the mesencepha-lon except for an unconnected hippocampal remnant. Seizures of several types and flattened or rarely paroxysmal EEGs have been described in hydranencephaly, but in none did autopsy show as incomplete a central nervous system as in the present case. Epileptic foci and neonatal seizures indistinguishable from those in which brain formation is normal may occur at a brainstem level when telencephalon and diencephalon are absent. Dener-vation and aberrant regeneration are possible epileptogenic mechanisms in the immature brain stem of this child.