RT Journal Article
SR Electronic
T1 Oral corticosteroids in the treatment of ocular myasthenia gravis
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 795
OP 795
DO 10.1212/WNL.24.8.795
VO 24
IS 8
A1 KENNETH C. FISCHER
A1 ROBERT J. SCHWARTZMAN
YR 1974
UL http://n.neurology.org/content/24/8/795.abstract
AB Eight patients with ocular myasthenia gravis unresponsive to anticholines-terase medications were treated with alternate-day prednisone. Seven of the eight showed significant and sustained improvement. The patients exhibited few side effects of steroid therapy, and none manifested neurologic deterioration after institution of the therapy. Since anticholines-terase medications fail to benefit most patients with ocular myasthenia and since these agents reportedly have long-term undesirable effects on the neuromuscular junction, oral prednisone is proposed as an alternative therapy for ocular myasthenia.