RT Journal Article SR Electronic T1 Neurogenic influence on local cerebral blood flow JF Neurology JO Neurology FD Lippincott Williams & Wilkins SP 954 OP 954 DO 10.1212/WNL.25.10.954 VO 25 IS 10 A1 SERCOMBE, R. A1 AUBINEAU, P. A1 EDVINSSON, L. A1 MAMO, H. A1 OWMAN, CH. A1 PINARD, E. A1 SEYLAZ, J. YR 1975 UL http://n.neurology.org/content/25/10/954.abstract AB Local cerebral blood flow was measured continuously in conscious rabbits (thermoclearance technique), and PaO2 and PaCO2 were recorded by mass spectrometry. Though inhalation of CO2 increased flow in caudate nucleus and lateral geniculate body, catecholamines only had effect on caudate nucleus where isoproterenolenhanced and epinephrine and norepinephrine reduced flow. Reduction by electrical stimulation of the neck sympathetic trunk was particularly evident in the caudate. Blood flow increased markedly in both regions after preganglionic conduction blockade. The effects were correlated with a significantly lower degree of sympathetic arteriolar innervation (fluorescence histochemistry) in the lateral geniculate body compared with the caudate nucleus.