RT Journal Article
SR Electronic
T1 Neurogenic influence on local cerebral blood flow
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 954
OP 954
DO 10.1212/WNL.25.10.954
VO 25
IS 10
A1 SERCOMBE, R.
A1 AUBINEAU, P.
A1 EDVINSSON, L.
A1 MAMO, H.
A1 OWMAN, CH.
A1 PINARD, E.
A1 SEYLAZ, J.
YR 1975
UL http://n.neurology.org/content/25/10/954.abstract
AB Local cerebral blood flow was measured continuously in conscious rabbits (thermoclearance technique), and PaO2 and PaCO2 were recorded by mass spectrometry. Though inhalation of CO2 increased flow in caudate nucleus and lateral geniculate body, catecholamines only had effect on caudate nucleus where isoproterenolenhanced and epinephrine and norepinephrine reduced flow. Reduction by electrical stimulation of the neck sympathetic trunk was particularly evident in the caudate. Blood flow increased markedly in both regions after preganglionic conduction blockade. The effects were correlated with a significantly lower degree of sympathetic arteriolar innervation (fluorescence histochemistry) in the lateral geniculate body compared with the caudate nucleus.