RT Journal Article
SR Electronic
T1 Neuropathologic changes in ataxia‐telangiectasia
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 947
OP 947
DO 10.1212/WNL.26.10.947
VO 26
IS 10
A1 DE LEON, GUILLERMO A.
A1 GROVER, WARREN D.
A1 HUFF, DALE S.
YR 1976
UL http://n.neurology.org/content/26/10/947.abstract
AB The neuropathologic findings in a 17-year-old boy with ataxia-telangiectasia are described. In agreement with previous reports, pathologic changes were present in the cerebellum, spinal cord, dorsal root ganglia, and striated muscle. The lesions in the spinal cord and dorsal root ganglia were more severe than previously described. Abnormalities were also seen in several brain stem nuclei, including the mesencephalic nucleus of the trigeminus and the substantia nigra. In addition, a small hamartomatous tumor was found in the thalamus.