PT  - JOURNAL ARTICLE
AU  - RICHARD G. BANT A
AU  - WILLIAM R. MARKESBERY
TI  - Elevated manganese levels associated with dementia and extrapyramidal signs
AID  - 10.1212/WNL.27.3.213
DP  - 1977 Mar 01
TA  - Neurology
PG  - 213--213
VI  - 27
IP  - 3
4099  - http://n.neurology.org/content/27/3/213.short
4100  - http://n.neurology.org/content/27/3/213.full
SO  - Neurology1977 Mar 01; 27
AB  - In a patient with elevated manganese levels, dementia, and an extrapyramidal syndrome, brain biopsy showed numerous neuritic plaques and neurofibrillary tangles typical of Alzheimer's disease. Manganese was elevated beyond toxic levels in serum, hair, urine, feces, and brain. The possible relationship of elevated manganese levels, dementia, and the extrapyramidal syndrome warrants further studies of similar cases.