PT - JOURNAL ARTICLE AU - DEWEY K. ZIEGLER AU - ROBERTA STEWART TI - Failure of tyramine to induce migraine AID - 10.1212/WNL.27.8.725 DP - 1977 Aug 01 TA - Neurology PG - 725--725 VI - 27 IP - 8 4099 - http://n.neurology.org/content/27/8/725.short 4100 - http://n.neurology.org/content/27/8/725.full SO - Neurology1977 Aug 01; 27 AB - In a double-blind study of 80 migraine patients, headache was precipitated by ingestion of 200 mg tyramine and not by placebo in eight individuals, but retesting of seven of these patients did not produce the same result. Placebo produced as severe headache as tyramine and in an even larger number of patients. It is concluded that dietary tyramine alone is rarely, if ever, the major precipitant of a migraine attack, although the possibility remains that it has such a role in the presence of particular physiologic states.