RT Journal Article
SR Electronic
T1 Failure of tyramine to induce migraine
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 725
OP 725
DO 10.1212/WNL.27.8.725
VO 27
IS 8
A1 DEWEY K. ZIEGLER
A1 ROBERTA STEWART
YR 1977
UL http://n.neurology.org/content/27/8/725.abstract
AB In a double-blind study of 80 migraine patients, headache was precipitated by ingestion of 200 mg tyramine and not by placebo in eight individuals, but retesting of seven of these patients did not produce the same result. Placebo produced as severe headache as tyramine and in an even larger number of patients. It is concluded that dietary tyramine alone is rarely, if ever, the major precipitant of a migraine attack, although the possibility remains that it has such a role in the presence of particular physiologic states.