PT  - JOURNAL ARTICLE
AU  - WILLIAM C. ROBERTSON, Jr.
AU  - MANUEL R. GOMEZ
AU  - DAVID F. REESE
AU  - HARUO OKAZAKI
TI  - Computerized tomography in demyelinating disease of the young
AID  - 10.1212/WNL.27.9.838
DP  - 1977 Sep 01
TA  - Neurology
PG  - 838--838
VI  - 27
IP  - 9
4099  - http://n.neurology.org/content/27/9/838.short
4100  - http://n.neurology.org/content/27/9/838.full
SO  - Neurology1977 Sep 01; 27
AB  - We have used computerized tomography (CT) to look for evidence of cerebral demyelination in children with progressive neurologic disorders. Fourteen patients with a clinical diagnosis of a demyelinating disorder were examined by CT, and five had CT findings suggesting cerebral demyelination. In two patients with a so-called myelinoclastic demyelinating disease, CT showed asymmetric, circumscribed areas of diminished radiodensity, and in three patients with a leukodystrophy, scans showed diffuse symmetric areas of low density in the centrum ovale. Autopsy examination in one patient confirmed the diagnosis of sudanophilic leukodystrophy and substantiated the abnormalities suspected from CT.