PT  - JOURNAL ARTICLE
AU  - Susac, John O.
AU  - Hardman, John M.
AU  - Selhorst, John B.
TI  - Microangiopathy of the brain and retina
AID  - 10.1212/WNL.29.3.313
DP  - 1979 Mar 01
TA  - Neurology
PG  - 313--313
VI  - 29
IP  - 3
4099  - http://n.neurology.org/content/29/3/313.short
4100  - http://n.neurology.org/content/29/3/313.full
SO  - Neurology1979 Mar 01; 29
AB  - Two, women (26 and 40 years old) developed an unusual microangopathy that affected the brain and retina. Psychiatric symptoms initially overshadowed the subacute features of the progressive neurologic disorder. Ophthalmoscopic findings of multifocal branch retinal artery occlusions provided clinical evidence of vasculopathy. Laboratory data did not reveal evidence of the known vasculitides, including systemic lupus erythematosus (SLE) arid syphilis. Cerebral angiography suggested vasculitis in the younger patient. Brain biopsy in the older patient (after 3 months of steroid therapy) revealed a sclerosis of the small pial and cortical vessels that was consistent with a “healed angiitis”. Both patients seemed to respond to steroid therapy.