RT Journal Article
SR Electronic
T1 Neuropsychologic impairment in astxocytoma survivors
JF Neurology
JO Neurology
FD Lippincott Williams & Wilkins
SP 172
OP 172
DO 10.1212/WNL.30.2.172
VO 30
IS 2
A1 Fred H. Hochberg
A1 Bennett Slotnick
YR 1980
UL http://n.neurology.org/content/30/2/172.abstract
AB Thirteen patients selected for long-term survival with primary astrocytic tumor (who failed to return to premorbid educational or vocational levels) were examined by neuropsychologic tests of specific and generalized higher cortical functions. In the absence of tumor regrowth or other neurologic disorders, each demonstrated difficulty in problem solving or coping with novel situations when previously acquired abilities, overlearned material, and psychometric intelligence appeared consistent with their premorbid level. The diffuse difficulties were unrelated to tumor type or location, and were not explicable by existing focal deficits, psychotic or depressive thought disorders, metabolic difficulties, or hydrocephalus. These examinations explained in part why these patients failed to resume active social lives or premorbid employment. The diffuse cortical dysfunction was most notable on the Category Test, Trails B, and Localization component of the Tactual Performance Test.